Ajulemic acid: A novel cannabinoid produces analgesia without a “high”

A long-standing goal in cannabinoid research has been the discovery of potent synthetic analogs of the natural substances that might be developed as clinically useful drugs. This requires, among other things, that they be free of the psychotropic effects that characterize the recreational use of Can...

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Veröffentlicht in:	Life sciences (1973) 2004-08, Vol.75 (12), p.1513-1522
Hauptverfasser:	Burstein, Sumner H, Karst, Matthias, Schneider, Udo, Zurier, Robert B
Format:	Artikel
Sprache:	eng
Schlagworte:	Ajulemic acid Analgesics - therapeutic use Anti-Inflammatory Agents - therapeutic use Cannabinoid Cannabis - chemistry Dronabinol - analogs & derivatives Dronabinol - chemistry Dronabinol - metabolism Dronabinol - therapeutic use Drug Design Inflammation Pain Pain - drug therapy Receptors, Cytoplasmic and Nuclear - metabolism Transcription Factors - metabolism
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