Prognostic significance of matrix metalloproteinase-2, cathepsin D, and tenascin-C expression in colorectal carcinoma

Matrix metalloproteinase-2 (MMP-2) and cathepsin D (CD) play a significant role in degrading the components of basement membrane and extracellular matrix (ECM), whereas tenascin-C (TN-C) is a glycoprotein of the ECM related to cell adhesion and detachment. These proteins have been implicated in tumo...

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Veröffentlicht in:	Pathology, research and practice research and practice, 2004-01, Vol.200 (5), p.379-387
Hauptverfasser:	Sis, Banu, Saǧol, Özgul, Küpelioǧlu, Ali, Sokmen, Selman, Terzi, Cem, Fuzun, Mehmet, Özer, Erdener, Bishop, Paul
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - metabolism Adult Aged Aged, 80 and over Biomarkers, Tumor - analysis Cathepsin D - biosynthesis Cathepsin-D Colorectal carcinoma Colorectal Neoplasms - metabolism Colorectal Neoplasms - mortality Colorectal Neoplasms - pathology Female History, 17th Century Humans Immunohistochemistry Lymphatic Metastasis - pathology Male Matrix Metalloproteinase 2 - biosynthesis Matrix metalloproteinase-2 Prognosis Survival Analysis Tenascin - biosynthesis Tenascin-C
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