B lymphocytes as antigen-presenting cell-based genetic vaccines

Inoculation of plasmid DNA is a simple way to immunize, but it is characterized by low immunogenicity, which has hampered the development of effective DNA vaccines for human use. Here, we discuss how poor immunogenicity can be solved and present our proposal: genetically programmed B lymphocytes as...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Immunological reviews 2004-06, Vol.199 (1), p.264-278
Hauptverfasser:	Zanetti, Maurizio, Castiglioni, Paola, Rizzi, Marta, Wheeler, Matthew, Gerloni, Mara
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigen Presentation - immunology B-Lymphocytes - immunology B-Lymphocytes - transplantation Dendritic Cells - immunology Humans Mice Mice, Transgenic Orthomyxoviridae - immunology Vaccination - methods Vaccines, DNA - immunology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!