Renal accumulation and excretion of radioiodinated 3-iodo-alpha-methyl-L-tyrosine

We investigated mechanisms of renal accumulation of radioiodinated 3-iodo-alpha-methyl-L-tyrosine (IMT), which has been used clinically for tumor imaging and as an amino acid transport marker in studies of brain and pancreas function. In this study, we used 125I- or 123I-labeled IMT ([125I]IMT or [1...

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Veröffentlicht in:	Annals of nuclear medicine 2004-05, Vol.18 (3), p.263-270
Hauptverfasser:	Shikano, Naoto, Kawai, Keiichi, Nakajima, Syuichi, Nishii, Ryuichi, Flores, 2nd, Leo Garcia, Kubodera, Akiko, Kubota, Nobuo, Ishikawa, Nobuyoshi, Saji, Hideo
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Line Dogs Epithelial Cells - diagnostic imaging Epithelial Cells - metabolism Epithelial Cells - secretion Humans Hydrogen-Ion Concentration Kidney - diagnostic imaging Kidney - metabolism Kidney - secretion Methyltyrosines - pharmacokinetics Methyltyrosines - secretion Mice Organ Specificity Radionuclide Imaging Radiopharmaceuticals - pharmacokinetics Rats Reproducibility of Results Tissue Distribution
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