Modification of buccal drug delivery following pretreatment with skin penetration enhancers

The effect of the lipophilic skin penetration enhancers octisalate (OS), padimate O (PO), and Azone® (AZ) on in vitro buccal permeability was assessed using caffeine (CAF), estradiol (E2), and triamcinolone acetonide (TAC) as model permeants. Buccal permeability was assessed in modified Ussing chamb...

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Veröffentlicht in:	Journal of pharmaceutical sciences 2004-08, Vol.93 (8), p.2054-2063
Hauptverfasser:	Nicolazzo, Joseph A., Reed, Barry L., Finnin, Barrie C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences buccal mucosa caffeine Cheek Drug Administration Routes drug permeability estradiol General pharmacology Medical sciences partition coefficient penetration enhancers Permeability Pharmaceutical technology. Pharmaceutical industry Pharmacology. Drug treatments Serum Albumin, Bovine - chemistry Skin Absorption Solubility Swine tissue retention triamcinolone acetonide
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