Topical prophylaxis with moxifloxacin prevents endophthalmitis in a rabbit model

The prophylaxis potential of the topical antibiotic, 0.5% moxifloxacin (Vigamox), was evaluated to prevent endophthalmitis after bacterial anterior chamber challenge in a rabbit model. An in vivo laboratory investigation. Three regimens of topical 0.5% moxifloxacin were tested for prophylaxis to pre...

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Veröffentlicht in:	American journal of ophthalmology 2004-07, Vol.138 (1), p.33-37
Hauptverfasser:	Kowalski, Regis P., Romanowski, Eric G., Mah, Francis S., Yates, Kathleen A., Gordon, Y.Jerold
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Topical Animals Anterior Chamber - drug effects Anterior Chamber - microbiology Antibiotics Aza Compounds - administration & dosage Biological and medical sciences Disease Models, Animal Endophthalmitis - microbiology Endophthalmitis - prevention & control Eye Eye Infections, Bacterial - microbiology Eye Infections, Bacterial - prevention & control FDA approval Fluoroquinolones Medical sciences Ophthalmic Solutions - administration & dosage Pharmacology. Drug treatments Quinolines - administration & dosage Rabbits Staphylococcal Infections - microbiology Staphylococcal Infections - prevention & control Staphylococcus aureus - isolation & purification Statistical analysis Studies
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