Pharmacokinetics of lopinavir in HIV type-1-infected children taking the new tablet formulation once daily

Recently, a new tablet formulation of the widely used HIV protease inhibitor lopinavir/ritonavir was licensed. Here, we present a pilot study of the pharmacokinetics of the new adult tablet formulation taken once daily in children. Lopinavir pharmacokinetics of the new adult tablet formulation were...

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Veröffentlicht in:	Antiviral therapy 2008-01, Vol.13 (8), p.1087-1090
Hauptverfasser:	VAN DER FLIER, Michiel, VERWEEL, Gwenda, VAN DER KNAAP, Linda C, VAN JAARSVELD, Petronette, DRIESSEN, Gert-Jan, VAN DER LEE, Manon, HARTWIG, Nico G, BURGER, David M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Anti-HIV Agents - administration & dosage Anti-HIV Agents - blood Anti-HIV Agents - pharmacokinetics Anti-HIV Agents - therapeutic use Antibiotics. Antiinfectious agents. Antiparasitic agents Antiviral agents Area Under Curve Biological and medical sciences Child Child, Preschool Drug Administration Schedule Female Half-Life HIV Infections - drug therapy HIV-1 - classification Human immunodeficiency virus Human viral diseases Humans Immunodeficiencies Immunodeficiencies. Immunoglobulinopathies Immunopathology Infectious diseases Lopinavir Male Medical sciences Pharmacology. Drug treatments Pyrimidinones - administration & dosage Pyrimidinones - blood Pyrimidinones - pharmacokinetics Pyrimidinones - therapeutic use Tablets Viral diseases Viral diseases of the lymphoid tissue and the blood. Aids
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