Reactive Hemophagocytic syndrome
We describe two cases of Reactive Hemophagocytic syndrome (RHS) occurring in rheumatic diseases in childhood. Patient 1, an adolescent girl with systemic onset Juvenile idopathic arthritis (JRA) presented like severe sepsis with shock, hepatic dysfunction and coagulopathy. Patient 2 presented with c...
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| Veröffentlicht in: | Indian journal of pediatrics 2008-12, Vol.75 (12), p.1261-1263 |
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| container_end_page | 1263 |
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| container_issue | 12 |
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| container_title | Indian journal of pediatrics |
| container_volume | 75 |
| creator | Rajam, L. Prasad, Vinitha Yatheesha, B.L. |
| description | We describe two cases of Reactive Hemophagocytic syndrome (RHS) occurring in rheumatic diseases in childhood. Patient 1, an adolescent girl with systemic onset Juvenile idopathic arthritis (JRA) presented like severe sepsis with shock, hepatic dysfunction and coagulopathy. Patient 2 presented with cardiac tamponade, she was later detected to have systemic lupus erythematosus (SLE). Her bone marrow aspirate revealed prominent hemophagocytosis. Both cases improved with pulse methylprednisolone therapy. |
| doi_str_mv | 10.1007/s12098-008-0170-y |
| format | Article |
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Patient 1, an adolescent girl with systemic onset Juvenile idopathic arthritis (JRA) presented like severe sepsis with shock, hepatic dysfunction and coagulopathy. Patient 2 presented with cardiac tamponade, she was later detected to have systemic lupus erythematosus (SLE). Her bone marrow aspirate revealed prominent hemophagocytosis. Both cases improved with pulse methylprednisolone therapy.</description><identifier>ISSN: 0019-5456</identifier><identifier>EISSN: 0973-7693</identifier><identifier>DOI: 10.1007/s12098-008-0170-y</identifier><identifier>PMID: 18810357</identifier><identifier>CODEN: IJPEA2</identifier><language>eng</language><publisher>New Delhi: Springer India</publisher><subject>Adolescent ; Arthritis, Juvenile - complications ; Biological and medical sciences ; Blood Coagulation Disorders - etiology ; Cardiac Tamponade - etiology ; Cardiology. Vascular system ; Clinical Brief ; Dermatology ; Diseases of the pericardium ; Female ; General aspects ; Glucocorticoids - administration & dosage ; Gynecology ; Heart ; Humans ; Liver - physiopathology ; Lupus Erythematosus, Systemic - complications ; Lymphohistiocytosis, Hemophagocytic - complications ; Lymphohistiocytosis, Hemophagocytic - drug therapy ; Lymphohistiocytosis, Hemophagocytic - etiology ; Lymphohistiocytosis, Hemophagocytic - physiopathology ; Medical sciences ; Medicine ; Medicine & Public Health ; Methylprednisolone - administration & dosage ; Pediatrics ; Pulse Therapy, Drug ; Skin involvement in other diseases. Miscellaneous. 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Patient 1, an adolescent girl with systemic onset Juvenile idopathic arthritis (JRA) presented like severe sepsis with shock, hepatic dysfunction and coagulopathy. Patient 2 presented with cardiac tamponade, she was later detected to have systemic lupus erythematosus (SLE). Her bone marrow aspirate revealed prominent hemophagocytosis. Both cases improved with pulse methylprednisolone therapy.</description><subject>Adolescent</subject><subject>Arthritis, Juvenile - complications</subject><subject>Biological and medical sciences</subject><subject>Blood Coagulation Disorders - etiology</subject><subject>Cardiac Tamponade - etiology</subject><subject>Cardiology. Vascular system</subject><subject>Clinical Brief</subject><subject>Dermatology</subject><subject>Diseases of the pericardium</subject><subject>Female</subject><subject>General aspects</subject><subject>Glucocorticoids - administration & dosage</subject><subject>Gynecology</subject><subject>Heart</subject><subject>Humans</subject><subject>Liver - physiopathology</subject><subject>Lupus Erythematosus, Systemic - complications</subject><subject>Lymphohistiocytosis, Hemophagocytic - complications</subject><subject>Lymphohistiocytosis, Hemophagocytic - drug therapy</subject><subject>Lymphohistiocytosis, Hemophagocytic - etiology</subject><subject>Lymphohistiocytosis, Hemophagocytic - physiopathology</subject><subject>Medical sciences</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Methylprednisolone - administration & dosage</subject><subject>Pediatrics</subject><subject>Pulse Therapy, Drug</subject><subject>Skin involvement in other diseases. Miscellaneous. General aspects</subject><issn>0019-5456</issn><issn>0973-7693</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE1LxDAQhoMorq7-AC-yF71VJ20-mqMs6goLgug5ZNPJ2qUfa9IK_fdmadGbh2EG5pl54SHkisIdBZD3gaag8gQgFpWQDEfkDJTMEilUdhxnoCrhjIsZOQ9hB5AqEOqUzGieU8i4PCOLNzS2K79xscK63X-abWuHrrSLMDSFb2u8ICfOVAEvpz4nH0-P78tVsn59flk-rBObybRLbB6zlHGOUckL57jaoOImL3hh5IY5K4UEynJkhUOQWMQ15CLllkOWOpXNye34d-_brx5Dp-syWKwq02DbBy2EkFQoFkE6gta3IXh0eu_L2vhBU9AHLXrUoqMWfdCih3hzPT3vNzUWfxeThwjcTIAJ1lTOm8aW4ZdLaSaBSR65dORCXDVb9HrX9r6JYv5J_wEjEXn4</recordid><startdate>20081201</startdate><enddate>20081201</enddate><creator>Rajam, L.</creator><creator>Prasad, Vinitha</creator><creator>Yatheesha, B.L.</creator><general>Springer India</general><general>Springer</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20081201</creationdate><title>Reactive Hemophagocytic syndrome</title><author>Rajam, L. ; Prasad, Vinitha ; Yatheesha, B.L.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c372t-c80199aff4175dff59be95a8d5da7b4fc7670148e4dfe07edbe908625c5032f93</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Adolescent</topic><topic>Arthritis, Juvenile - complications</topic><topic>Biological and medical sciences</topic><topic>Blood Coagulation Disorders - etiology</topic><topic>Cardiac Tamponade - etiology</topic><topic>Cardiology. Vascular system</topic><topic>Clinical Brief</topic><topic>Dermatology</topic><topic>Diseases of the pericardium</topic><topic>Female</topic><topic>General aspects</topic><topic>Glucocorticoids - administration & dosage</topic><topic>Gynecology</topic><topic>Heart</topic><topic>Humans</topic><topic>Liver - physiopathology</topic><topic>Lupus Erythematosus, Systemic - complications</topic><topic>Lymphohistiocytosis, Hemophagocytic - complications</topic><topic>Lymphohistiocytosis, Hemophagocytic - drug therapy</topic><topic>Lymphohistiocytosis, Hemophagocytic - etiology</topic><topic>Lymphohistiocytosis, Hemophagocytic - physiopathology</topic><topic>Medical sciences</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Methylprednisolone - administration & dosage</topic><topic>Pediatrics</topic><topic>Pulse Therapy, Drug</topic><topic>Skin involvement in other diseases. Miscellaneous. General aspects</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Rajam, L.</creatorcontrib><creatorcontrib>Prasad, Vinitha</creatorcontrib><creatorcontrib>Yatheesha, B.L.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Indian journal of pediatrics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Rajam, L.</au><au>Prasad, Vinitha</au><au>Yatheesha, B.L.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Reactive Hemophagocytic syndrome</atitle><jtitle>Indian journal of pediatrics</jtitle><stitle>Indian J Pediatr</stitle><addtitle>Indian J Pediatr</addtitle><date>2008-12-01</date><risdate>2008</risdate><volume>75</volume><issue>12</issue><spage>1261</spage><epage>1263</epage><pages>1261-1263</pages><issn>0019-5456</issn><eissn>0973-7693</eissn><coden>IJPEA2</coden><abstract>We describe two cases of Reactive Hemophagocytic syndrome (RHS) occurring in rheumatic diseases in childhood. Patient 1, an adolescent girl with systemic onset Juvenile idopathic arthritis (JRA) presented like severe sepsis with shock, hepatic dysfunction and coagulopathy. Patient 2 presented with cardiac tamponade, she was later detected to have systemic lupus erythematosus (SLE). Her bone marrow aspirate revealed prominent hemophagocytosis. Both cases improved with pulse methylprednisolone therapy.</abstract><cop>New Delhi</cop><pub>Springer India</pub><pmid>18810357</pmid><doi>10.1007/s12098-008-0170-y</doi><tpages>3</tpages></addata></record> |
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| ispartof | Indian journal of pediatrics, 2008-12, Vol.75 (12), p.1261-1263 |
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| source | MEDLINE; Alma/SFX Local Collection; SpringerLink Journals - AutoHoldings |
| subjects | Adolescent Arthritis, Juvenile - complications Biological and medical sciences Blood Coagulation Disorders - etiology Cardiac Tamponade - etiology Cardiology. Vascular system Clinical Brief Dermatology Diseases of the pericardium Female General aspects Glucocorticoids - administration & dosage Gynecology Heart Humans Liver - physiopathology Lupus Erythematosus, Systemic - complications Lymphohistiocytosis, Hemophagocytic - complications Lymphohistiocytosis, Hemophagocytic - drug therapy Lymphohistiocytosis, Hemophagocytic - etiology Lymphohistiocytosis, Hemophagocytic - physiopathology Medical sciences Medicine Medicine & Public Health Methylprednisolone - administration & dosage Pediatrics Pulse Therapy, Drug Skin involvement in other diseases. Miscellaneous. General aspects |
| title | Reactive Hemophagocytic syndrome |
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