5-Exo-dig Radical Cyclization of Enediynes:  The First Synthesis of Tin-Substituted Benzofulvenes

5-Exo-dig Radical Cyclization of Enediynes:  The First Synthesis of Tin-Substituted Benzofulvenes

Bu3Sn-mediated 5-exo-dig radical cyclization of diaryl enediynes provides a mild and efficient approach to tin-substituted fulvenes. Further synthetic opportunities opened by this process and general factors responsible for the observed regio- and stereoselectivity are outlined.

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Organic letters 2004-07, Vol.6 (14), p.2457-2460
Hauptverfasser: Kovalenko, Serguei V, Peabody, Scott, Manoharan, Mariappan, Clark, Ronald J, Alabugin, Igor V
Format: Artikel
Sprache:eng
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Bu3Sn-mediated 5-exo-dig radical cyclization of diaryl enediynes provides a mild and efficient approach to tin-substituted fulvenes. Further synthetic opportunities opened by this process and general factors responsible for the observed regio- and stereoselectivity are outlined.
ISSN:1523-7060
1523-7052
DOI:10.1021/ol049122c