Possible linkage between specific histological structures and aberrant reactivation of the Wnt pathway in adamantinomatous craniopharyngioma

This study concerns the significance of nuclear/cytoplasmic expression of beta‐catenin and mutation of the beta‐catenin gene in craniopharyngiomas. Fourteen adamantinomatous type and one squamous papillary type craniopharyngiomas were studied. Histologically, 13 of 14 adamantinomatous type craniopha...

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Veröffentlicht in:	The Journal of pathology 2004-07, Vol.203 (3), p.814-821
Hauptverfasser:	Kato, Keisuke, Nakatani, Yukio, Kanno, Hiroshi, Inayama, Yoshiyuki, Ijiri, Rieko, Nagahara, Noriyuki, Miyake, Tetsumi, Tanaka, Mio, Ito, Yumi, Aida, Noriko, Tachibana, Katsuhiko, Sekido, Ken-ichi, Tanaka, Yukichi
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Base Sequence beta Catenin Biological and medical sciences Child Child, Preschool craniopharyngioma Craniopharyngioma - genetics Craniopharyngioma - metabolism Craniopharyngioma - pathology Cytoskeletal Proteins - genetics Cytoskeletal Proteins - metabolism DNA Mutational Analysis - methods DNA, Neoplasm - genetics Female Humans Immunoenzyme Techniques Infant Investigative techniques, diagnostic techniques (general aspects) Ki-67 Antigen - metabolism Male Medical sciences Middle Aged Mutation Neoplasm Proteins - metabolism Neoplasm Proteins - physiology Neurology Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Pituitary Neoplasms - genetics Pituitary Neoplasms - metabolism Pituitary Neoplasms - pathology Proto-Oncogene Proteins - physiology Signal Transduction Trans-Activators - genetics Trans-Activators - metabolism Tumors of the nervous system. Phacomatoses Wnt Proteins Wnt signal
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