Toward brain imaging of serotonin 5-HT1A autoreceptor internalization

Enhancing cerebral serotonin (5-hydroxytryptamine, 5-HT) neurotransmission is a common property of antidepressant treatments and the basis for their efficacy. 5-HT1A receptors located on the cell body and dendrites of 5-HT neurons (autoreceptors) play a key role in this regard. Because they normally...

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Veröffentlicht in:	NeuroImage (Orlando, Fla.) Fla.), 2004-07, Vol.22 (3), p.1421-1426
Hauptverfasser:	Zimmer, L, Riad, M, Rbah, L, Belkacem-Kahlouli, A, Le Bars, D, Renaud, B, Descarries, L
Format:	Artikel
Sprache:	eng
Schlagworte:	8-Hydroxy-2-(di-n-propylamino)tetralin - pharmacology Animals Autoradiography Autoreceptors - metabolism Binding Sites Brain - metabolism Brain - ultrastructure Cell Membrane - metabolism Cytoplasm - metabolism Experiments Extracellular Fluid - metabolism Kinetics Ligands Male Microdialysis Microscopy Microscopy, Immunoelectron Osmolar Concentration Piperazines - pharmacology Pyridines - pharmacology Raphe Nuclei - metabolism Rats Rats, Sprague-Dawley Receptor, Serotonin, 5-HT1A - metabolism Rodents Serotonin Antagonists - pharmacology Serotonin Receptor Agonists - pharmacology Subcellular Fractions - metabolism Tissue Distribution
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