Cutaneous Alternaria infection in renal transplant recipients: a report of two cases with an unusual mode of transmission

: We report two cases of cutaneous alternariosis in renal transplant recipients. The diagnosis was made by mycologic and histologic examination. The patients were treated with itraconazole. In one patient who had undergone surgical resection of the cutaneous lesion along with antifungal treatment, t...

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Veröffentlicht in:Transplant infectious disease 2004-03, Vol.6 (1), p.46-49
Hauptverfasser: Kazory, A., Ducloux, D., Reboux, G., Blanc, D., Faivre, B., Chalopin, J.‐M., Piarroux, R.
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container_end_page 49
container_issue 1
container_start_page 46
container_title Transplant infectious disease
container_volume 6
creator Kazory, A.
Ducloux, D.
Reboux, G.
Blanc, D.
Faivre, B.
Chalopin, J.‐M.
Piarroux, R.
description : We report two cases of cutaneous alternariosis in renal transplant recipients. The diagnosis was made by mycologic and histologic examination. The patients were treated with itraconazole. In one patient who had undergone surgical resection of the cutaneous lesion along with antifungal treatment, the follow‐up period was uneventful with no signs of recurrence. In the other patient, surgical excision of the lesion was not performed prior to antifungal therapy. The lesion disappeared following treatment but local recurrence was observed 1.5 years later with an unfavorable evolution despite administration of the second course of therapy. Resection of the lesion and prolongation of the treatment resulted in a satisfactory course with no signs of local recurrence over a follow‐up period of 4.5 years. Interestingly, both of the patients had a previous history of a mild traumatic event with a stretcher in our outpatient clinic where the follow‐up visits were made. A vast mycologic survey was then made in our department, which disclosed that some of the stretchers were contaminated by the fungi and could have potentially served as the reservoirs and vectors for the transmission of the fungus.
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The diagnosis was made by mycologic and histologic examination. The patients were treated with itraconazole. In one patient who had undergone surgical resection of the cutaneous lesion along with antifungal treatment, the follow‐up period was uneventful with no signs of recurrence. In the other patient, surgical excision of the lesion was not performed prior to antifungal therapy. The lesion disappeared following treatment but local recurrence was observed 1.5 years later with an unfavorable evolution despite administration of the second course of therapy. Resection of the lesion and prolongation of the treatment resulted in a satisfactory course with no signs of local recurrence over a follow‐up period of 4.5 years. Interestingly, both of the patients had a previous history of a mild traumatic event with a stretcher in our outpatient clinic where the follow‐up visits were made. 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source Wiley Online Library - AutoHoldings Journals; MEDLINE
subjects Adult
Alternaria
Alternaria - isolation & purification
Cross Infection - microbiology
Cross Infection - transmission
Dermatomycoses - microbiology
Dermatomycoses - transmission
Equipment and Supplies, Hospital - microbiology
Equipment Contamination
fungal infection
Humans
Kidney Transplantation - adverse effects
Male
Middle Aged
renal transplant
title Cutaneous Alternaria infection in renal transplant recipients: a report of two cases with an unusual mode of transmission
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