Leishmanicidal activity of phenylene bridged C2 symmetric glycosyl ureides

A series of phenylene bridged C 2 symmetric glycosyl ureides were synthesised and evaluated against Leishmania donovani and two of them reduced the dose of standard drug SSG. A number of phenylene bridged C 2 symmetric glycosyl uerides with ester ( 3a– f), alcohol ( 4a– c) and acid ( 5a– d) function...

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Veröffentlicht in:	Bioorganic & medicinal chemistry letters 2004-08, Vol.14 (15), p.4055-4059
Hauptverfasser:	Tewari, Neetu, Ramesh, Mishra, R.C, Tripathi, R.P, Srivastava, V.M.L, Gupta, Suman
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibiotics. Antiinfectious agents. Antiparasitic agents Antiparasitic agents Antiprotozoal Agents - chemical synthesis Antiprotozoal Agents - pharmacology Biological and medical sciences Leishmania - drug effects Medical sciences Miscellaneous Models, Molecular Molecular Conformation Pharmacology. Drug treatments Structure-Activity Relationship
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