Prospects and implications of using chromatin insulators in gene therapy and transgenesis

Gene therapy has emerged from the idea of inserting a wild‐type copy of a gene in order to restore the proper expression and function of a damaged gene. Initial efforts have focused on finding the proper vector and delivery method to introduce a corrected gene to the affected tissue or cell type. Ev...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	BioEssays 2004-07, Vol.26 (7), p.796-807
Hauptverfasser:	Recillas-Targa, Félix, Valadez-Graham, Viviana, Farrell, Catherine M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Chromatin - genetics Chromatin - physiology Gene Transfer Techniques Genetic Therapy - methods Genetic Vectors - genetics Humans Insulator Elements - genetics Transgenes - genetics
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!