New transport peptides broaden the horizon of applications for peptidic pharmaceuticals

Protein transduction domains (PTDs) have proven to be an invaluable tool to transduce a wide variety of cargo's including peptides across the plasma membrane and into intact tissue. The PTDs are able to deliver biologically active molecules both in vitro and in vivo. This study describes many n...

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Veröffentlicht in:	Molecular diversity 2004, Vol.8 (2), p.101-111
Hauptverfasser:	Langedijk, J P M, Olijhoek, T, Schut, D, Autar, R, Meloen, R H
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals beta-Galactosidase - genetics beta-Galactosidase - metabolism Binding Sites Carrier Proteins - genetics Carrier Proteins - metabolism Cattle Cells, Cultured Fluorescein-5-isothiocyanate - chemistry Fluorescein-5-isothiocyanate - metabolism Fluoresceins - chemistry Fluoresceins - metabolism Fluorescent Dyes - chemistry Fluorescent Dyes - metabolism Galactosides - chemistry Galactosides - metabolism Gene Products, tat - genetics Gene Products, tat - metabolism Heparin - metabolism Horseradish Peroxidase - genetics Horseradish Peroxidase - metabolism Membrane Glycoproteins - genetics Membrane Glycoproteins - metabolism Molecular Biology - methods Molecular Sequence Data Peptide Mapping Peptides Peptides - analysis Peptides - genetics Peptides - metabolism Protein Engineering - methods Protein Structure, Tertiary Protein Transport Streptavidin - chemistry Streptavidin - metabolism Viral Envelope Proteins - genetics Viral Envelope Proteins - metabolism
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