Effect of sodium valproate on esophageal motility in healthy subjects and patients with gastroesophageal reflux

There is experimental evidence to show that upper gastrointestinal tract motility is influenced by a GABAergic mechanism. Sodium valproate acts as a GABA agonist, and has been proven to affect the human internal anal sphincter. The aim of this study was to evaluate any possible effect of sodium valp...

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Veröffentlicht in:	Scandinavian journal of gastroenterology 2004-06, Vol.39 (6), p.521-526
Hauptverfasser:	TZOVARAS, G, TSIAOUSSIS, J, ATHANASAKIS, E, ZORAS, O, XYNOS, E, CHRYSOS, E
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Biological and medical sciences Esophagus Esophagus - drug effects Esophagus - physiopathology Female GABA Agents - pharmacology Gastroenterology. Liver. Pancreas. Abdomen Gastroesophageal Reflux - physiopathology Hernia, Hiatal - physiopathology Humans Male Manometry Medical sciences Middle Aged Monitoring, Ambulatory Other diseases. Semiology Postprandial Period Valproic Acid - pharmacology
Online-Zugang:	Volltext
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