Chronic Pancreatitis in the Elderly in Japan
Background/Aim: Although the elderly comprise an increasingly large segment of the population, little has been written about chronic pancreatitis in this age group in Japan. In this study, we analyzed the clinical features of elderly Japanese patients with chronic pancreatitis and compared them with...
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Veröffentlicht in: | Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2004-01, Vol.4 (3-4), p.223-228 |
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container_title | Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] |
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creator | Kamisawa, Terumi Yoshiike, Masami Egawa, Naoto Nakajima, Hitoshi Tsuruta, Kouji Okamoto, Atsutake Nakamura, Teruo |
description | Background/Aim: Although the elderly comprise an increasingly large segment of the population, little has been written about chronic pancreatitis in this age group in Japan. In this study, we analyzed the clinical features of elderly Japanese patients with chronic pancreatitis and compared them with those of late-onset chronic pancreatitis patients in Western countries. Methods: Subjects were 182 patients (162 males and 20 females) with chronic pancreatitis. They were divided into two groups: early-onset group (onset 60 years in 94% of the cases. The late-onset group was more likely to have painless disease, and calcification of the pancreas and steatorrhea were rare in this group. Major causes of death were malignancy and malnutrition in each group. Conclusions: Early- and lateonset chronic pancreatitis showed different clinical features. Clinicians should consider autoimmune pancreatitis in the differential diagnosis in elderly patients with obstructive jaundice. |
doi_str_mv | 10.1159/000078433 |
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In this study, we analyzed the clinical features of elderly Japanese patients with chronic pancreatitis and compared them with those of late-onset chronic pancreatitis patients in Western countries. Methods: Subjects were 182 patients (162 males and 20 females) with chronic pancreatitis. They were divided into two groups: early-onset group (onset <65 years of age, n = 119) and late-onset group (onset ≥65 years of age, n = 63). Clinical findings and follow-up data were examined for each group. Results: Alcohol abuse was the most common etiological factor in early-onset pancreatitis patients. In the late-onset group, the frequencies of idiopathic and autoimmune pancreatitis increased. Furthermore, the age at onset of autoimmune pancreatitis was >60 years in 94% of the cases. The late-onset group was more likely to have painless disease, and calcification of the pancreas and steatorrhea were rare in this group. Major causes of death were malignancy and malnutrition in each group. Conclusions: Early- and lateonset chronic pancreatitis showed different clinical features. Clinicians should consider autoimmune pancreatitis in the differential diagnosis in elderly patients with obstructive jaundice.</description><identifier>ISSN: 1424-3903</identifier><identifier>EISSN: 1424-3911</identifier><identifier>DOI: 10.1159/000078433</identifier><identifier>PMID: 15148441</identifier><language>eng</language><publisher>Basel, Switzerland: Elsevier B.V</publisher><subject>Age Factors ; Aged ; Autoimmune pancreatitis, elderly Japanese ; Chronic Disease ; Chronic pancreatitis, elderly Japanese ; Elderly Japanese, chronic pancreatitis ; Female ; Follow-Up Studies ; Humans ; Japan - epidemiology ; Male ; Middle Aged ; Original Paper ; Pancreatitis - etiology ; Pancreatitis - mortality ; Pancreatitis - pathology ; Survival Rate ; Western World</subject><ispartof>Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], 2004-01, Vol.4 (3-4), p.223-228</ispartof><rights>2004 IAP and EPC. Published by Elsevier India, a division of Reed Elsevier India Pvt. Ltd.</rights><rights>2004 S. Karger AG, Basel and IAP</rights><rights>Copyright 2004 S. Karger AG, Basel and IAP</rights><rights>Copyright (c) 2004 S. Karger AG, Basel</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c496t-60dbc5a63c9d71ff99239acc1630f54e1516c744e8d25c4458b36d57dac847603</citedby><cites>FETCH-LOGICAL-c496t-60dbc5a63c9d71ff99239acc1630f54e1516c744e8d25c4458b36d57dac847603</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,2429,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15148441$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kamisawa, Terumi</creatorcontrib><creatorcontrib>Yoshiike, Masami</creatorcontrib><creatorcontrib>Egawa, Naoto</creatorcontrib><creatorcontrib>Nakajima, Hitoshi</creatorcontrib><creatorcontrib>Tsuruta, Kouji</creatorcontrib><creatorcontrib>Okamoto, Atsutake</creatorcontrib><creatorcontrib>Nakamura, Teruo</creatorcontrib><title>Chronic Pancreatitis in the Elderly in Japan</title><title>Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]</title><addtitle>Pancreatology</addtitle><description>Background/Aim: Although the elderly comprise an increasingly large segment of the population, little has been written about chronic pancreatitis in this age group in Japan. In this study, we analyzed the clinical features of elderly Japanese patients with chronic pancreatitis and compared them with those of late-onset chronic pancreatitis patients in Western countries. Methods: Subjects were 182 patients (162 males and 20 females) with chronic pancreatitis. They were divided into two groups: early-onset group (onset <65 years of age, n = 119) and late-onset group (onset ≥65 years of age, n = 63). Clinical findings and follow-up data were examined for each group. Results: Alcohol abuse was the most common etiological factor in early-onset pancreatitis patients. In the late-onset group, the frequencies of idiopathic and autoimmune pancreatitis increased. Furthermore, the age at onset of autoimmune pancreatitis was >60 years in 94% of the cases. The late-onset group was more likely to have painless disease, and calcification of the pancreas and steatorrhea were rare in this group. Major causes of death were malignancy and malnutrition in each group. Conclusions: Early- and lateonset chronic pancreatitis showed different clinical features. Clinicians should consider autoimmune pancreatitis in the differential diagnosis in elderly patients with obstructive jaundice.</description><subject>Age Factors</subject><subject>Aged</subject><subject>Autoimmune pancreatitis, elderly Japanese</subject><subject>Chronic Disease</subject><subject>Chronic pancreatitis, elderly Japanese</subject><subject>Elderly Japanese, chronic pancreatitis</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Humans</subject><subject>Japan - epidemiology</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Original Paper</subject><subject>Pancreatitis - etiology</subject><subject>Pancreatitis - mortality</subject><subject>Pancreatitis - pathology</subject><subject>Survival Rate</subject><subject>Western World</subject><issn>1424-3903</issn><issn>1424-3911</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqF0E1LwzAYB_AgipvTg2dByg6CYDXvbY9jzDeG7qDnkCWpy-zambTCvr2ZnRNkYC5JyC_Pk_wBOEXwGiGW3cAwkpQSsge6iGIakwyh_e0akg448n4OIcYIZYeggxiiKaWoC66GM1eVVkUTWSpnZG1r6yNbRvXMRKNCG1es1ttHuZTlMTjIZeHNyWbugdfb0cvwPh4_3z0MB-NY0YzXMYd6qpjkRGU6QXmeZZhkUinECcwZNaE7VwmlJtWYKUpZOiVcs0RLldKEQ9IDF23dpas-GuNrsbBemaKQpakaLzjnDDNC_oUYwYRhjgPs_4HzqnFl-ITAGCcp4ZQHdNki5SrvncnF0tmFdCuBoFgHLbZBB3u-KdhMF0b_yk2yAZy14F26N-O24Od6f-fpZPD0DcRS5wGRFpmQ9acNzCtrSmW0dUbVQld2x8u-AO_xmaw</recordid><startdate>20040101</startdate><enddate>20040101</enddate><creator>Kamisawa, Terumi</creator><creator>Yoshiike, Masami</creator><creator>Egawa, Naoto</creator><creator>Nakajima, Hitoshi</creator><creator>Tsuruta, Kouji</creator><creator>Okamoto, Atsutake</creator><creator>Nakamura, Teruo</creator><general>Elsevier B.V</general><general>Elsevier Limited</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>H94</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7QP</scope><scope>7X8</scope></search><sort><creationdate>20040101</creationdate><title>Chronic Pancreatitis in the Elderly in Japan</title><author>Kamisawa, Terumi ; Yoshiike, Masami ; Egawa, Naoto ; Nakajima, Hitoshi ; Tsuruta, Kouji ; Okamoto, Atsutake ; Nakamura, Teruo</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c496t-60dbc5a63c9d71ff99239acc1630f54e1516c744e8d25c4458b36d57dac847603</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2004</creationdate><topic>Age Factors</topic><topic>Aged</topic><topic>Autoimmune pancreatitis, elderly Japanese</topic><topic>Chronic Disease</topic><topic>Chronic pancreatitis, elderly Japanese</topic><topic>Elderly Japanese, chronic pancreatitis</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Humans</topic><topic>Japan - epidemiology</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Original Paper</topic><topic>Pancreatitis - etiology</topic><topic>Pancreatitis - mortality</topic><topic>Pancreatitis - pathology</topic><topic>Survival Rate</topic><topic>Western World</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kamisawa, Terumi</creatorcontrib><creatorcontrib>Yoshiike, Masami</creatorcontrib><creatorcontrib>Egawa, Naoto</creatorcontrib><creatorcontrib>Nakajima, Hitoshi</creatorcontrib><creatorcontrib>Tsuruta, Kouji</creatorcontrib><creatorcontrib>Okamoto, Atsutake</creatorcontrib><creatorcontrib>Nakamura, Teruo</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kamisawa, Terumi</au><au>Yoshiike, Masami</au><au>Egawa, Naoto</au><au>Nakajima, Hitoshi</au><au>Tsuruta, Kouji</au><au>Okamoto, Atsutake</au><au>Nakamura, Teruo</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Chronic Pancreatitis in the Elderly in Japan</atitle><jtitle>Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]</jtitle><addtitle>Pancreatology</addtitle><date>2004-01-01</date><risdate>2004</risdate><volume>4</volume><issue>3-4</issue><spage>223</spage><epage>228</epage><pages>223-228</pages><issn>1424-3903</issn><eissn>1424-3911</eissn><abstract>Background/Aim: Although the elderly comprise an increasingly large segment of the population, little has been written about chronic pancreatitis in this age group in Japan. In this study, we analyzed the clinical features of elderly Japanese patients with chronic pancreatitis and compared them with those of late-onset chronic pancreatitis patients in Western countries. Methods: Subjects were 182 patients (162 males and 20 females) with chronic pancreatitis. They were divided into two groups: early-onset group (onset <65 years of age, n = 119) and late-onset group (onset ≥65 years of age, n = 63). Clinical findings and follow-up data were examined for each group. Results: Alcohol abuse was the most common etiological factor in early-onset pancreatitis patients. In the late-onset group, the frequencies of idiopathic and autoimmune pancreatitis increased. Furthermore, the age at onset of autoimmune pancreatitis was >60 years in 94% of the cases. The late-onset group was more likely to have painless disease, and calcification of the pancreas and steatorrhea were rare in this group. Major causes of death were malignancy and malnutrition in each group. Conclusions: Early- and lateonset chronic pancreatitis showed different clinical features. Clinicians should consider autoimmune pancreatitis in the differential diagnosis in elderly patients with obstructive jaundice.</abstract><cop>Basel, Switzerland</cop><pub>Elsevier B.V</pub><pmid>15148441</pmid><doi>10.1159/000078433</doi><tpages>6</tpages></addata></record> |
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subjects | Age Factors Aged Autoimmune pancreatitis, elderly Japanese Chronic Disease Chronic pancreatitis, elderly Japanese Elderly Japanese, chronic pancreatitis Female Follow-Up Studies Humans Japan - epidemiology Male Middle Aged Original Paper Pancreatitis - etiology Pancreatitis - mortality Pancreatitis - pathology Survival Rate Western World |
title | Chronic Pancreatitis in the Elderly in Japan |
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