Comparison of perfusion computed tomography and computed tomography angiography source images with perfusion-weighted imaging and diffusion-weighted imaging in patients with acute stroke of less than 6 hours' duration
We aimed to determine the diagnostic value of perfusion computed tomography (PCT) and CT angiography (CTA) including CTA source images (CTA-SI) in comparison with perfusion-weighted magnetic resonance imaging (MRI) (PWI) and diffusion-weighted MRI (DWI) in acute stroke
Gespeichert in:
| Veröffentlicht in: | Stroke (1970) 2004-07, Vol.35 (7), p.1652-1658 |
|---|---|
| Hauptverfasser: | , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1658 |
|---|---|
| container_issue | 7 |
| container_start_page | 1652 |
| container_title | Stroke (1970) |
| container_volume | 35 |
| creator | Schramm, Peter Schellinger, Peter D Klotz, Ernst Kallenberg, Kai Fiebach, Jochen B Külkens, Sonja Heiland, Sabine Knauth, Michael Sartor, Klaus |
| description | We aimed to determine the diagnostic value of perfusion computed tomography (PCT) and CT angiography (CTA) including CTA source images (CTA-SI) in comparison with perfusion-weighted magnetic resonance imaging (MRI) (PWI) and diffusion-weighted MRI (DWI) in acute stroke |
| doi_str_mv | 10.1161/01.STR.0000131271.54098.22 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_66650919</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>66650919</sourcerecordid><originalsourceid>FETCH-LOGICAL-c335t-305604a51e8eeae87ccc7c43498527aae88a605acfcb3944ba0e0713ddde12553</originalsourceid><addsrcrecordid>eNp1Uctu1DAUtRCIDoVfQBYLWCX1OzE7NCoPqRJSW9aWx7lJDJM42I6qfmr_Bk87aFb1xva552HrIPSBkppSRS8IrW9ur2tSFuWUNbSWgui2ZuwF2lDJRCUUa1-iDSFcV0xofYbepPS78Blv5Wt0RiWVUiuxQQ_bMC02-hRmHHq8QOzX5MvFFXzN0OEcpjBEu4z32M7dM_jg_59TWKMD7Cc7QMJ3Po8n0-oO_DAexIexn4dHx873z439jBebPcz5aGVdycYpx_AHDu_dQ0o4j3bGCo8lOX3C3RqLJMxv0ave7hO8O-7n6NfXy9vt9-rq57cf2y9XleNc5ooTqYiwkkILYKFtnHONE1zoVrLGFqS1ikjrerfjWoidJUAayruuA8qk5Ofo45PvEsPfFVI2k08O9ns7Q1iTUUpJoqkuxM9PRBdDShF6s8Ty0XhvKDGHYg2hphRrTsWax2INY0X8_piy7iboTtJjk_wfhR6nFw</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>66650919</pqid></control><display><type>article</type><title>Comparison of perfusion computed tomography and computed tomography angiography source images with perfusion-weighted imaging and diffusion-weighted imaging in patients with acute stroke of less than 6 hours' duration</title><source>MEDLINE</source><source>American Heart Association Journals</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>Journals@Ovid Complete</source><source>Alma/SFX Local Collection</source><creator>Schramm, Peter ; Schellinger, Peter D ; Klotz, Ernst ; Kallenberg, Kai ; Fiebach, Jochen B ; Külkens, Sonja ; Heiland, Sabine ; Knauth, Michael ; Sartor, Klaus</creator><creatorcontrib>Schramm, Peter ; Schellinger, Peter D ; Klotz, Ernst ; Kallenberg, Kai ; Fiebach, Jochen B ; Külkens, Sonja ; Heiland, Sabine ; Knauth, Michael ; Sartor, Klaus</creatorcontrib><description>We aimed to determine the diagnostic value of perfusion computed tomography (PCT) and CT angiography (CTA) including CTA source images (CTA-SI) in comparison with perfusion-weighted magnetic resonance imaging (MRI) (PWI) and diffusion-weighted MRI (DWI) in acute stroke <6 hours.
Noncontrast-enhanced CT, PCT, CTA, stroke MRI, including PWI and DWI, and MR angiography (MRA), were performed in patients with symptoms of acute stroke lasting <6 hours. We analyzed ischemic lesion volumes on patients' arrival as shown on NECT, PCT, CTA-SI, DWI, and PWI (Wilcoxon, Spearman, Bland-Altman) and compared them to the infarct extent as shown on day 5 NECT.
Twenty-two stroke patients underwent CT and MRI scanning within 6 hours. PCT time to peak (PCT-TTP) volumes did not differ from PWI-TTP (P=0.686 for patients who did not undergo thrombolysis/P=0.328 for patients who underwent thrombolysis), nor did PCT cerebral blood volume (PCT-CBV) differ from PWI-CBV (P=0.893/P=0.169). CTA-SI volumes did not differ from DWI volumes (P=0.465/P=0.086). Lesion volumes measured in PCT maps significantly correlated with lesion volumes on PWI (P=0.0047, r=1.0/P=0.0019, r=0.897 for TTP; P=0.0054, r=0.983/P=0.0026, r=0.871 for CBV). Also, PCT-CBV lesion volumes significantly correlated with follow-up CT lesion volumes (P=0.0047, r=1.0/P=0.0046, r=0.819).
In hyperacute stroke, the combination of PCT and CTA can render important diagnostic information regarding the infarct extent and the perfusion deficit. Lesions on PCT-TTP and PCT-CBV do not differ from lesions on PWI-TTP and PWI-CBV; lesions on CTA source images do not differ from lesions on DWI. The combination of noncontrast-enhanced CT (NECT), perfusion CT (PCT), and CT angiography (CTA) can render additional information within <15 minutes and may help in therapeutic decision-making if PWI and DWI are not available or cannot be performed on specific patients.</description><identifier>ISSN: 0039-2499</identifier><identifier>EISSN: 1524-4628</identifier><identifier>DOI: 10.1161/01.STR.0000131271.54098.22</identifier><identifier>PMID: 15155964</identifier><language>eng</language><publisher>United States</publisher><subject>Adult ; Aged ; Aged, 80 and over ; Brain - diagnostic imaging ; Brain - pathology ; Cerebral Angiography ; Diffusion Magnetic Resonance Imaging ; Female ; Humans ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Stroke - diagnosis ; Stroke - diagnostic imaging ; Time Factors ; Tomography, X-Ray Computed</subject><ispartof>Stroke (1970), 2004-07, Vol.35 (7), p.1652-1658</ispartof><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c335t-305604a51e8eeae87ccc7c43498527aae88a605acfcb3944ba0e0713ddde12553</citedby><cites>FETCH-LOGICAL-c335t-305604a51e8eeae87ccc7c43498527aae88a605acfcb3944ba0e0713ddde12553</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,3687,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15155964$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Schramm, Peter</creatorcontrib><creatorcontrib>Schellinger, Peter D</creatorcontrib><creatorcontrib>Klotz, Ernst</creatorcontrib><creatorcontrib>Kallenberg, Kai</creatorcontrib><creatorcontrib>Fiebach, Jochen B</creatorcontrib><creatorcontrib>Külkens, Sonja</creatorcontrib><creatorcontrib>Heiland, Sabine</creatorcontrib><creatorcontrib>Knauth, Michael</creatorcontrib><creatorcontrib>Sartor, Klaus</creatorcontrib><title>Comparison of perfusion computed tomography and computed tomography angiography source images with perfusion-weighted imaging and diffusion-weighted imaging in patients with acute stroke of less than 6 hours' duration</title><title>Stroke (1970)</title><addtitle>Stroke</addtitle><description>We aimed to determine the diagnostic value of perfusion computed tomography (PCT) and CT angiography (CTA) including CTA source images (CTA-SI) in comparison with perfusion-weighted magnetic resonance imaging (MRI) (PWI) and diffusion-weighted MRI (DWI) in acute stroke <6 hours.
Noncontrast-enhanced CT, PCT, CTA, stroke MRI, including PWI and DWI, and MR angiography (MRA), were performed in patients with symptoms of acute stroke lasting <6 hours. We analyzed ischemic lesion volumes on patients' arrival as shown on NECT, PCT, CTA-SI, DWI, and PWI (Wilcoxon, Spearman, Bland-Altman) and compared them to the infarct extent as shown on day 5 NECT.
Twenty-two stroke patients underwent CT and MRI scanning within 6 hours. PCT time to peak (PCT-TTP) volumes did not differ from PWI-TTP (P=0.686 for patients who did not undergo thrombolysis/P=0.328 for patients who underwent thrombolysis), nor did PCT cerebral blood volume (PCT-CBV) differ from PWI-CBV (P=0.893/P=0.169). CTA-SI volumes did not differ from DWI volumes (P=0.465/P=0.086). Lesion volumes measured in PCT maps significantly correlated with lesion volumes on PWI (P=0.0047, r=1.0/P=0.0019, r=0.897 for TTP; P=0.0054, r=0.983/P=0.0026, r=0.871 for CBV). Also, PCT-CBV lesion volumes significantly correlated with follow-up CT lesion volumes (P=0.0047, r=1.0/P=0.0046, r=0.819).
In hyperacute stroke, the combination of PCT and CTA can render important diagnostic information regarding the infarct extent and the perfusion deficit. Lesions on PCT-TTP and PCT-CBV do not differ from lesions on PWI-TTP and PWI-CBV; lesions on CTA source images do not differ from lesions on DWI. The combination of noncontrast-enhanced CT (NECT), perfusion CT (PCT), and CT angiography (CTA) can render additional information within <15 minutes and may help in therapeutic decision-making if PWI and DWI are not available or cannot be performed on specific patients.</description><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Brain - diagnostic imaging</subject><subject>Brain - pathology</subject><subject>Cerebral Angiography</subject><subject>Diffusion Magnetic Resonance Imaging</subject><subject>Female</subject><subject>Humans</subject><subject>Magnetic Resonance Imaging</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Stroke - diagnosis</subject><subject>Stroke - diagnostic imaging</subject><subject>Time Factors</subject><subject>Tomography, X-Ray Computed</subject><issn>0039-2499</issn><issn>1524-4628</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1Uctu1DAUtRCIDoVfQBYLWCX1OzE7NCoPqRJSW9aWx7lJDJM42I6qfmr_Bk87aFb1xva552HrIPSBkppSRS8IrW9ur2tSFuWUNbSWgui2ZuwF2lDJRCUUa1-iDSFcV0xofYbepPS78Blv5Wt0RiWVUiuxQQ_bMC02-hRmHHq8QOzX5MvFFXzN0OEcpjBEu4z32M7dM_jg_59TWKMD7Cc7QMJ3Po8n0-oO_DAexIexn4dHx873z439jBebPcz5aGVdycYpx_AHDu_dQ0o4j3bGCo8lOX3C3RqLJMxv0ave7hO8O-7n6NfXy9vt9-rq57cf2y9XleNc5ooTqYiwkkILYKFtnHONE1zoVrLGFqS1ikjrerfjWoidJUAayruuA8qk5Ofo45PvEsPfFVI2k08O9ns7Q1iTUUpJoqkuxM9PRBdDShF6s8Ty0XhvKDGHYg2hphRrTsWax2INY0X8_piy7iboTtJjk_wfhR6nFw</recordid><startdate>200407</startdate><enddate>200407</enddate><creator>Schramm, Peter</creator><creator>Schellinger, Peter D</creator><creator>Klotz, Ernst</creator><creator>Kallenberg, Kai</creator><creator>Fiebach, Jochen B</creator><creator>Külkens, Sonja</creator><creator>Heiland, Sabine</creator><creator>Knauth, Michael</creator><creator>Sartor, Klaus</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200407</creationdate><title>Comparison of perfusion computed tomography and computed tomography angiography source images with perfusion-weighted imaging and diffusion-weighted imaging in patients with acute stroke of less than 6 hours' duration</title><author>Schramm, Peter ; Schellinger, Peter D ; Klotz, Ernst ; Kallenberg, Kai ; Fiebach, Jochen B ; Külkens, Sonja ; Heiland, Sabine ; Knauth, Michael ; Sartor, Klaus</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c335t-305604a51e8eeae87ccc7c43498527aae88a605acfcb3944ba0e0713ddde12553</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2004</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Brain - diagnostic imaging</topic><topic>Brain - pathology</topic><topic>Cerebral Angiography</topic><topic>Diffusion Magnetic Resonance Imaging</topic><topic>Female</topic><topic>Humans</topic><topic>Magnetic Resonance Imaging</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Stroke - diagnosis</topic><topic>Stroke - diagnostic imaging</topic><topic>Time Factors</topic><topic>Tomography, X-Ray Computed</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Schramm, Peter</creatorcontrib><creatorcontrib>Schellinger, Peter D</creatorcontrib><creatorcontrib>Klotz, Ernst</creatorcontrib><creatorcontrib>Kallenberg, Kai</creatorcontrib><creatorcontrib>Fiebach, Jochen B</creatorcontrib><creatorcontrib>Külkens, Sonja</creatorcontrib><creatorcontrib>Heiland, Sabine</creatorcontrib><creatorcontrib>Knauth, Michael</creatorcontrib><creatorcontrib>Sartor, Klaus</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Stroke (1970)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Schramm, Peter</au><au>Schellinger, Peter D</au><au>Klotz, Ernst</au><au>Kallenberg, Kai</au><au>Fiebach, Jochen B</au><au>Külkens, Sonja</au><au>Heiland, Sabine</au><au>Knauth, Michael</au><au>Sartor, Klaus</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Comparison of perfusion computed tomography and computed tomography angiography source images with perfusion-weighted imaging and diffusion-weighted imaging in patients with acute stroke of less than 6 hours' duration</atitle><jtitle>Stroke (1970)</jtitle><addtitle>Stroke</addtitle><date>2004-07</date><risdate>2004</risdate><volume>35</volume><issue>7</issue><spage>1652</spage><epage>1658</epage><pages>1652-1658</pages><issn>0039-2499</issn><eissn>1524-4628</eissn><abstract>We aimed to determine the diagnostic value of perfusion computed tomography (PCT) and CT angiography (CTA) including CTA source images (CTA-SI) in comparison with perfusion-weighted magnetic resonance imaging (MRI) (PWI) and diffusion-weighted MRI (DWI) in acute stroke <6 hours.
Noncontrast-enhanced CT, PCT, CTA, stroke MRI, including PWI and DWI, and MR angiography (MRA), were performed in patients with symptoms of acute stroke lasting <6 hours. We analyzed ischemic lesion volumes on patients' arrival as shown on NECT, PCT, CTA-SI, DWI, and PWI (Wilcoxon, Spearman, Bland-Altman) and compared them to the infarct extent as shown on day 5 NECT.
Twenty-two stroke patients underwent CT and MRI scanning within 6 hours. PCT time to peak (PCT-TTP) volumes did not differ from PWI-TTP (P=0.686 for patients who did not undergo thrombolysis/P=0.328 for patients who underwent thrombolysis), nor did PCT cerebral blood volume (PCT-CBV) differ from PWI-CBV (P=0.893/P=0.169). CTA-SI volumes did not differ from DWI volumes (P=0.465/P=0.086). Lesion volumes measured in PCT maps significantly correlated with lesion volumes on PWI (P=0.0047, r=1.0/P=0.0019, r=0.897 for TTP; P=0.0054, r=0.983/P=0.0026, r=0.871 for CBV). Also, PCT-CBV lesion volumes significantly correlated with follow-up CT lesion volumes (P=0.0047, r=1.0/P=0.0046, r=0.819).
In hyperacute stroke, the combination of PCT and CTA can render important diagnostic information regarding the infarct extent and the perfusion deficit. Lesions on PCT-TTP and PCT-CBV do not differ from lesions on PWI-TTP and PWI-CBV; lesions on CTA source images do not differ from lesions on DWI. The combination of noncontrast-enhanced CT (NECT), perfusion CT (PCT), and CT angiography (CTA) can render additional information within <15 minutes and may help in therapeutic decision-making if PWI and DWI are not available or cannot be performed on specific patients.</abstract><cop>United States</cop><pmid>15155964</pmid><doi>10.1161/01.STR.0000131271.54098.22</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0039-2499 |
| ispartof | Stroke (1970), 2004-07, Vol.35 (7), p.1652-1658 |
| issn | 0039-2499 1524-4628 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_66650919 |
| source | MEDLINE; American Heart Association Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Journals@Ovid Complete; Alma/SFX Local Collection |
| subjects | Adult Aged Aged, 80 and over Brain - diagnostic imaging Brain - pathology Cerebral Angiography Diffusion Magnetic Resonance Imaging Female Humans Magnetic Resonance Imaging Male Middle Aged Stroke - diagnosis Stroke - diagnostic imaging Time Factors Tomography, X-Ray Computed |
| title | Comparison of perfusion computed tomography and computed tomography angiography source images with perfusion-weighted imaging and diffusion-weighted imaging in patients with acute stroke of less than 6 hours' duration |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-07T00%3A33%3A14IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Comparison%20of%20perfusion%20computed%20tomography%20and%20computed%20tomography%20angiography%20source%20images%20with%20perfusion-weighted%20imaging%20and%20diffusion-weighted%20imaging%20in%20patients%20with%20acute%20stroke%20of%20less%20than%206%20hours'%20duration&rft.jtitle=Stroke%20(1970)&rft.au=Schramm,%20Peter&rft.date=2004-07&rft.volume=35&rft.issue=7&rft.spage=1652&rft.epage=1658&rft.pages=1652-1658&rft.issn=0039-2499&rft.eissn=1524-4628&rft_id=info:doi/10.1161/01.STR.0000131271.54098.22&rft_dat=%3Cproquest_cross%3E66650919%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=66650919&rft_id=info:pmid/15155964&rfr_iscdi=true |