Choroidal neovascularization after laser in situ keratomileusis in a patient with presumed ocular histoplasmosis syndrome

A 44-year-old patient with presumed ocular histoplasmosis syndrome (POHS) who developed a choroidal neovascular membrane (CNV) after laser in situ keratomileusis (LASIK) surgery is presented. A 44-year-old male patient with moderate myopia and POHS who underwent LASIK surgery complained of distorted vision after the procedure. He had a quiet POHS lesion prior to refractive surgery. Fundus examination and fluorescein angiography revealed subfoveal CNV after the LASIK surgery. He underwent 2 sessions of photodynamic therapy (PDT). Subfoveal CNV involuted after PDT and his vision improved from 20/300 to 20/25 at 13 months follow-up. CNV can be triggered by LASIK surgery in patients with POHS. Those patients should be made aware of and closely followed up postoperatively for this complication.