Homocysteine levels in newly admitted schizophrenic patients
We previously found a marked elevation of plasma homocysteine in young male schizophrenic patients in hospital. It seemed important to determine if this finding is already present in newly admitted schizophrenic patients. Serum homocysteine levels were studied in 184 consecutively admitted schizophr...
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Veröffentlicht in: | Journal of psychiatric research 2004-07, Vol.38 (4), p.413-416 |
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creator | Applebaum, Julia Shimon, Hady Sela, Ben-Ami Belmaker, R.H Levine, Joseph |
description | We previously found a marked elevation of plasma homocysteine in young male schizophrenic patients in hospital. It seemed important to determine if this finding is already present in newly admitted schizophrenic patients. Serum homocysteine levels were studied in 184 consecutively admitted schizophrenic patients and 305 control subjects from an employee screening program. Homocysteine levels were markedly increased in this population of newly admitted schizophrenic patients, especially in young males. Newly admitted male schizophrenic patients have elevated homocysteine levels that cannot be explained on the basis of poor hospital nutrition. Smoking may raise homocysteine by 1–2 μM/L but this is not a large enough effect to explain our findings. |
doi_str_mv | 10.1016/j.jpsychires.2004.01.003 |
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It seemed important to determine if this finding is already present in newly admitted schizophrenic patients. Serum homocysteine levels were studied in 184 consecutively admitted schizophrenic patients and 305 control subjects from an employee screening program. Homocysteine levels were markedly increased in this population of newly admitted schizophrenic patients, especially in young males. Newly admitted male schizophrenic patients have elevated homocysteine levels that cannot be explained on the basis of poor hospital nutrition. Smoking may raise homocysteine by 1–2 μM/L but this is not a large enough effect to explain our findings.</description><identifier>ISSN: 0022-3956</identifier><identifier>EISSN: 1879-1379</identifier><identifier>DOI: 10.1016/j.jpsychires.2004.01.003</identifier><identifier>PMID: 15203293</identifier><identifier>CODEN: JPYRA3</identifier><language>eng</language><publisher>Oxford: Elsevier Ltd</publisher><subject>Adult ; Age Factors ; Aged ; Biological and medical sciences ; Case-Control Studies ; Female ; Homocysteine - blood ; Humans ; Institution therapy. Inpatient treatment ; Male ; Medical sciences ; Middle Aged ; MTHFR ; Neurotoxicity ; Patient Admission ; Psychology. Psychoanalysis. Psychiatry ; Psychopathology. 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It seemed important to determine if this finding is already present in newly admitted schizophrenic patients. Serum homocysteine levels were studied in 184 consecutively admitted schizophrenic patients and 305 control subjects from an employee screening program. Homocysteine levels were markedly increased in this population of newly admitted schizophrenic patients, especially in young males. Newly admitted male schizophrenic patients have elevated homocysteine levels that cannot be explained on the basis of poor hospital nutrition. Smoking may raise homocysteine by 1–2 μM/L but this is not a large enough effect to explain our findings.</description><subject>Adult</subject><subject>Age Factors</subject><subject>Aged</subject><subject>Biological and medical sciences</subject><subject>Case-Control Studies</subject><subject>Female</subject><subject>Homocysteine - blood</subject><subject>Humans</subject><subject>Institution therapy. Inpatient treatment</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>MTHFR</subject><subject>Neurotoxicity</subject><subject>Patient Admission</subject><subject>Psychology. Psychoanalysis. Psychiatry</subject><subject>Psychopathology. Psychiatry</subject><subject>Schizophrenia</subject><subject>Schizophrenia - physiopathology</subject><subject>Serum homocysteine</subject><subject>Sex Factors</subject><subject>Smoking</subject><subject>Treatments</subject><issn>0022-3956</issn><issn>1879-1379</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkE1PwzAMhiMEgjH4C6gXuLU4TZquEhdAfElIXOAcZYmrZeoXcQcav55MmzRunOzDY7_2w1jCIePA1fUyWw60tgsfkLIcQGbAMwBxwCZ8VlYpF2V1yCYAeZ6KqlAn7JRoCQBlzuUxO-FFDiKvxITdPPdtb9c0ou8wafALG0p8l3T43awT41o_jugSilk__bAI2HmbDGb02I10xo5q0xCe7-qUfTw-vN8_p69vTy_3t6-plQBjKuZ1actaSZULVJUTHBTGThbS5SZeJAuUYN1cmgoLq0CKeSXAKVOWEoUVU3a13TuE_nOFNOrWk8WmMR32K9JKKTnj8Z8pm21BG3qigLUegm9NWGsOemNOL_XenN6Y08B1NBdHL3YZq3mLbj-4UxWByx1gyJqmDqaznv5wFZSFkpG723LRJH55DJpstGXRxUw7atf7_6_5BQL5kbY</recordid><startdate>20040701</startdate><enddate>20040701</enddate><creator>Applebaum, Julia</creator><creator>Shimon, Hady</creator><creator>Sela, Ben-Ami</creator><creator>Belmaker, R.H</creator><creator>Levine, Joseph</creator><general>Elsevier Ltd</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20040701</creationdate><title>Homocysteine levels in newly admitted schizophrenic patients</title><author>Applebaum, Julia ; Shimon, Hady ; Sela, Ben-Ami ; Belmaker, R.H ; Levine, Joseph</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c400t-3bf7c7f64623e69d3106e3e6454d2a21445e40cdb4a9e5c6043b930d6a774e3c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2004</creationdate><topic>Adult</topic><topic>Age Factors</topic><topic>Aged</topic><topic>Biological and medical sciences</topic><topic>Case-Control Studies</topic><topic>Female</topic><topic>Homocysteine - blood</topic><topic>Humans</topic><topic>Institution therapy. Inpatient treatment</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>MTHFR</topic><topic>Neurotoxicity</topic><topic>Patient Admission</topic><topic>Psychology. Psychoanalysis. Psychiatry</topic><topic>Psychopathology. Psychiatry</topic><topic>Schizophrenia</topic><topic>Schizophrenia - physiopathology</topic><topic>Serum homocysteine</topic><topic>Sex Factors</topic><topic>Smoking</topic><topic>Treatments</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Applebaum, Julia</creatorcontrib><creatorcontrib>Shimon, Hady</creatorcontrib><creatorcontrib>Sela, Ben-Ami</creatorcontrib><creatorcontrib>Belmaker, R.H</creatorcontrib><creatorcontrib>Levine, Joseph</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of psychiatric research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Applebaum, Julia</au><au>Shimon, Hady</au><au>Sela, Ben-Ami</au><au>Belmaker, R.H</au><au>Levine, Joseph</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Homocysteine levels in newly admitted schizophrenic patients</atitle><jtitle>Journal of psychiatric research</jtitle><addtitle>J Psychiatr Res</addtitle><date>2004-07-01</date><risdate>2004</risdate><volume>38</volume><issue>4</issue><spage>413</spage><epage>416</epage><pages>413-416</pages><issn>0022-3956</issn><eissn>1879-1379</eissn><coden>JPYRA3</coden><abstract>We previously found a marked elevation of plasma homocysteine in young male schizophrenic patients in hospital. It seemed important to determine if this finding is already present in newly admitted schizophrenic patients. Serum homocysteine levels were studied in 184 consecutively admitted schizophrenic patients and 305 control subjects from an employee screening program. Homocysteine levels were markedly increased in this population of newly admitted schizophrenic patients, especially in young males. Newly admitted male schizophrenic patients have elevated homocysteine levels that cannot be explained on the basis of poor hospital nutrition. Smoking may raise homocysteine by 1–2 μM/L but this is not a large enough effect to explain our findings.</abstract><cop>Oxford</cop><pub>Elsevier Ltd</pub><pmid>15203293</pmid><doi>10.1016/j.jpsychires.2004.01.003</doi><tpages>4</tpages></addata></record> |
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subjects | Adult Age Factors Aged Biological and medical sciences Case-Control Studies Female Homocysteine - blood Humans Institution therapy. Inpatient treatment Male Medical sciences Middle Aged MTHFR Neurotoxicity Patient Admission Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Schizophrenia Schizophrenia - physiopathology Serum homocysteine Sex Factors Smoking Treatments |
title | Homocysteine levels in newly admitted schizophrenic patients |
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