Homocysteine levels in newly admitted schizophrenic patients

We previously found a marked elevation of plasma homocysteine in young male schizophrenic patients in hospital. It seemed important to determine if this finding is already present in newly admitted schizophrenic patients. Serum homocysteine levels were studied in 184 consecutively admitted schizophr...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Journal of psychiatric research 2004-07, Vol.38 (4), p.413-416
Hauptverfasser: Applebaum, Julia, Shimon, Hady, Sela, Ben-Ami, Belmaker, R.H, Levine, Joseph
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 416
container_issue 4
container_start_page 413
container_title Journal of psychiatric research
container_volume 38
creator Applebaum, Julia
Shimon, Hady
Sela, Ben-Ami
Belmaker, R.H
Levine, Joseph
description We previously found a marked elevation of plasma homocysteine in young male schizophrenic patients in hospital. It seemed important to determine if this finding is already present in newly admitted schizophrenic patients. Serum homocysteine levels were studied in 184 consecutively admitted schizophrenic patients and 305 control subjects from an employee screening program. Homocysteine levels were markedly increased in this population of newly admitted schizophrenic patients, especially in young males. Newly admitted male schizophrenic patients have elevated homocysteine levels that cannot be explained on the basis of poor hospital nutrition. Smoking may raise homocysteine by 1–2 μM/L but this is not a large enough effect to explain our findings.
doi_str_mv 10.1016/j.jpsychires.2004.01.003
format Article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_66648129</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0022395604000056</els_id><sourcerecordid>66648129</sourcerecordid><originalsourceid>FETCH-LOGICAL-c400t-3bf7c7f64623e69d3106e3e6454d2a21445e40cdb4a9e5c6043b930d6a774e3c3</originalsourceid><addsrcrecordid>eNqFkE1PwzAMhiMEgjH4C6gXuLU4TZquEhdAfElIXOAcZYmrZeoXcQcav55MmzRunOzDY7_2w1jCIePA1fUyWw60tgsfkLIcQGbAMwBxwCZ8VlYpF2V1yCYAeZ6KqlAn7JRoCQBlzuUxO-FFDiKvxITdPPdtb9c0ou8wafALG0p8l3T43awT41o_jugSilk__bAI2HmbDGb02I10xo5q0xCe7-qUfTw-vN8_p69vTy_3t6-plQBjKuZ1actaSZULVJUTHBTGThbS5SZeJAuUYN1cmgoLq0CKeSXAKVOWEoUVU3a13TuE_nOFNOrWk8WmMR32K9JKKTnj8Z8pm21BG3qigLUegm9NWGsOemNOL_XenN6Y08B1NBdHL3YZq3mLbj-4UxWByx1gyJqmDqaznv5wFZSFkpG723LRJH55DJpstGXRxUw7atf7_6_5BQL5kbY</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>66648129</pqid></control><display><type>article</type><title>Homocysteine levels in newly admitted schizophrenic patients</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals</source><creator>Applebaum, Julia ; Shimon, Hady ; Sela, Ben-Ami ; Belmaker, R.H ; Levine, Joseph</creator><creatorcontrib>Applebaum, Julia ; Shimon, Hady ; Sela, Ben-Ami ; Belmaker, R.H ; Levine, Joseph</creatorcontrib><description>We previously found a marked elevation of plasma homocysteine in young male schizophrenic patients in hospital. It seemed important to determine if this finding is already present in newly admitted schizophrenic patients. Serum homocysteine levels were studied in 184 consecutively admitted schizophrenic patients and 305 control subjects from an employee screening program. Homocysteine levels were markedly increased in this population of newly admitted schizophrenic patients, especially in young males. Newly admitted male schizophrenic patients have elevated homocysteine levels that cannot be explained on the basis of poor hospital nutrition. Smoking may raise homocysteine by 1–2 μM/L but this is not a large enough effect to explain our findings.</description><identifier>ISSN: 0022-3956</identifier><identifier>EISSN: 1879-1379</identifier><identifier>DOI: 10.1016/j.jpsychires.2004.01.003</identifier><identifier>PMID: 15203293</identifier><identifier>CODEN: JPYRA3</identifier><language>eng</language><publisher>Oxford: Elsevier Ltd</publisher><subject>Adult ; Age Factors ; Aged ; Biological and medical sciences ; Case-Control Studies ; Female ; Homocysteine - blood ; Humans ; Institution therapy. Inpatient treatment ; Male ; Medical sciences ; Middle Aged ; MTHFR ; Neurotoxicity ; Patient Admission ; Psychology. Psychoanalysis. Psychiatry ; Psychopathology. Psychiatry ; Schizophrenia ; Schizophrenia - physiopathology ; Serum homocysteine ; Sex Factors ; Smoking ; Treatments</subject><ispartof>Journal of psychiatric research, 2004-07, Vol.38 (4), p.413-416</ispartof><rights>2004 Elsevier Ltd</rights><rights>2004 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c400t-3bf7c7f64623e69d3106e3e6454d2a21445e40cdb4a9e5c6043b930d6a774e3c3</citedby><cites>FETCH-LOGICAL-c400t-3bf7c7f64623e69d3106e3e6454d2a21445e40cdb4a9e5c6043b930d6a774e3c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.jpsychires.2004.01.003$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,777,781,3537,27905,27906,45976</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&amp;idt=15907564$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15203293$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Applebaum, Julia</creatorcontrib><creatorcontrib>Shimon, Hady</creatorcontrib><creatorcontrib>Sela, Ben-Ami</creatorcontrib><creatorcontrib>Belmaker, R.H</creatorcontrib><creatorcontrib>Levine, Joseph</creatorcontrib><title>Homocysteine levels in newly admitted schizophrenic patients</title><title>Journal of psychiatric research</title><addtitle>J Psychiatr Res</addtitle><description>We previously found a marked elevation of plasma homocysteine in young male schizophrenic patients in hospital. It seemed important to determine if this finding is already present in newly admitted schizophrenic patients. Serum homocysteine levels were studied in 184 consecutively admitted schizophrenic patients and 305 control subjects from an employee screening program. Homocysteine levels were markedly increased in this population of newly admitted schizophrenic patients, especially in young males. Newly admitted male schizophrenic patients have elevated homocysteine levels that cannot be explained on the basis of poor hospital nutrition. Smoking may raise homocysteine by 1–2 μM/L but this is not a large enough effect to explain our findings.</description><subject>Adult</subject><subject>Age Factors</subject><subject>Aged</subject><subject>Biological and medical sciences</subject><subject>Case-Control Studies</subject><subject>Female</subject><subject>Homocysteine - blood</subject><subject>Humans</subject><subject>Institution therapy. Inpatient treatment</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>MTHFR</subject><subject>Neurotoxicity</subject><subject>Patient Admission</subject><subject>Psychology. Psychoanalysis. Psychiatry</subject><subject>Psychopathology. Psychiatry</subject><subject>Schizophrenia</subject><subject>Schizophrenia - physiopathology</subject><subject>Serum homocysteine</subject><subject>Sex Factors</subject><subject>Smoking</subject><subject>Treatments</subject><issn>0022-3956</issn><issn>1879-1379</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkE1PwzAMhiMEgjH4C6gXuLU4TZquEhdAfElIXOAcZYmrZeoXcQcav55MmzRunOzDY7_2w1jCIePA1fUyWw60tgsfkLIcQGbAMwBxwCZ8VlYpF2V1yCYAeZ6KqlAn7JRoCQBlzuUxO-FFDiKvxITdPPdtb9c0ou8wafALG0p8l3T43awT41o_jugSilk__bAI2HmbDGb02I10xo5q0xCe7-qUfTw-vN8_p69vTy_3t6-plQBjKuZ1actaSZULVJUTHBTGThbS5SZeJAuUYN1cmgoLq0CKeSXAKVOWEoUVU3a13TuE_nOFNOrWk8WmMR32K9JKKTnj8Z8pm21BG3qigLUegm9NWGsOemNOL_XenN6Y08B1NBdHL3YZq3mLbj-4UxWByx1gyJqmDqaznv5wFZSFkpG723LRJH55DJpstGXRxUw7atf7_6_5BQL5kbY</recordid><startdate>20040701</startdate><enddate>20040701</enddate><creator>Applebaum, Julia</creator><creator>Shimon, Hady</creator><creator>Sela, Ben-Ami</creator><creator>Belmaker, R.H</creator><creator>Levine, Joseph</creator><general>Elsevier Ltd</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20040701</creationdate><title>Homocysteine levels in newly admitted schizophrenic patients</title><author>Applebaum, Julia ; Shimon, Hady ; Sela, Ben-Ami ; Belmaker, R.H ; Levine, Joseph</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c400t-3bf7c7f64623e69d3106e3e6454d2a21445e40cdb4a9e5c6043b930d6a774e3c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2004</creationdate><topic>Adult</topic><topic>Age Factors</topic><topic>Aged</topic><topic>Biological and medical sciences</topic><topic>Case-Control Studies</topic><topic>Female</topic><topic>Homocysteine - blood</topic><topic>Humans</topic><topic>Institution therapy. Inpatient treatment</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>MTHFR</topic><topic>Neurotoxicity</topic><topic>Patient Admission</topic><topic>Psychology. Psychoanalysis. Psychiatry</topic><topic>Psychopathology. Psychiatry</topic><topic>Schizophrenia</topic><topic>Schizophrenia - physiopathology</topic><topic>Serum homocysteine</topic><topic>Sex Factors</topic><topic>Smoking</topic><topic>Treatments</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Applebaum, Julia</creatorcontrib><creatorcontrib>Shimon, Hady</creatorcontrib><creatorcontrib>Sela, Ben-Ami</creatorcontrib><creatorcontrib>Belmaker, R.H</creatorcontrib><creatorcontrib>Levine, Joseph</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of psychiatric research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Applebaum, Julia</au><au>Shimon, Hady</au><au>Sela, Ben-Ami</au><au>Belmaker, R.H</au><au>Levine, Joseph</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Homocysteine levels in newly admitted schizophrenic patients</atitle><jtitle>Journal of psychiatric research</jtitle><addtitle>J Psychiatr Res</addtitle><date>2004-07-01</date><risdate>2004</risdate><volume>38</volume><issue>4</issue><spage>413</spage><epage>416</epage><pages>413-416</pages><issn>0022-3956</issn><eissn>1879-1379</eissn><coden>JPYRA3</coden><abstract>We previously found a marked elevation of plasma homocysteine in young male schizophrenic patients in hospital. It seemed important to determine if this finding is already present in newly admitted schizophrenic patients. Serum homocysteine levels were studied in 184 consecutively admitted schizophrenic patients and 305 control subjects from an employee screening program. Homocysteine levels were markedly increased in this population of newly admitted schizophrenic patients, especially in young males. Newly admitted male schizophrenic patients have elevated homocysteine levels that cannot be explained on the basis of poor hospital nutrition. Smoking may raise homocysteine by 1–2 μM/L but this is not a large enough effect to explain our findings.</abstract><cop>Oxford</cop><pub>Elsevier Ltd</pub><pmid>15203293</pmid><doi>10.1016/j.jpsychires.2004.01.003</doi><tpages>4</tpages></addata></record>
fulltext fulltext
identifier ISSN: 0022-3956
ispartof Journal of psychiatric research, 2004-07, Vol.38 (4), p.413-416
issn 0022-3956
1879-1379
language eng
recordid cdi_proquest_miscellaneous_66648129
source MEDLINE; Elsevier ScienceDirect Journals
subjects Adult
Age Factors
Aged
Biological and medical sciences
Case-Control Studies
Female
Homocysteine - blood
Humans
Institution therapy. Inpatient treatment
Male
Medical sciences
Middle Aged
MTHFR
Neurotoxicity
Patient Admission
Psychology. Psychoanalysis. Psychiatry
Psychopathology. Psychiatry
Schizophrenia
Schizophrenia - physiopathology
Serum homocysteine
Sex Factors
Smoking
Treatments
title Homocysteine levels in newly admitted schizophrenic patients
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-19T23%3A56%3A11IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Homocysteine%20levels%20in%20newly%20admitted%20schizophrenic%20patients&rft.jtitle=Journal%20of%20psychiatric%20research&rft.au=Applebaum,%20Julia&rft.date=2004-07-01&rft.volume=38&rft.issue=4&rft.spage=413&rft.epage=416&rft.pages=413-416&rft.issn=0022-3956&rft.eissn=1879-1379&rft.coden=JPYRA3&rft_id=info:doi/10.1016/j.jpsychires.2004.01.003&rft_dat=%3Cproquest_cross%3E66648129%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=66648129&rft_id=info:pmid/15203293&rft_els_id=S0022395604000056&rfr_iscdi=true