Impairment of B cell receptor‐mediated Ca2+ influx, activation of mitogen‐activated protein kinases and growth inhibition in CD72‐deficient BAL‐17 cells

CD72 is a 45 kDa B cell‐specific type II transmembrane protein of the C‐type lectin superfamily. It was originally defined as a receptor‐like molecule that regulates B cell activation and differentiation; however, its precise function remains unclear since more recent functional analyses, including...

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Veröffentlicht in:International immunology 2004-07, Vol.16 (7), p.971-982
Hauptverfasser: Ogimoto, Mami, Ichinowatari, Gaku, Watanabe, Noriyuki, Tada, Nobuhiko, Mizuno, Kazuya, Yakura, Hidetaka
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Sprache:eng
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