Cholesterol Efflux Alters Lipid Raft Stability and Distribution During Capacitation of Boar Spermatozoa

A reduction in plasma membrane cholesterol is one of the early events that either triggers or is closely associated with capacitation of mammalian spermatozoa. In this investigation, we have examined the effects of cholesterol efflux on tyrosine phosphorylation, lipid diffusion, and raft organizatio...

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Veröffentlicht in:	Biology of reproduction 2004-07, Vol.71 (1), p.253-265
Hauptverfasser:	SHADAN, Sadaf, JAMES, Peter S, HOWES, Elizabeth A, JONES, Roy
Format:	Artikel
Sprache:	eng
Schlagworte:	Acrosome Reaction - drug effects Animals beta-Cyclodextrins - pharmacology Biological and medical sciences Calcium - metabolism Cell Membrane - metabolism Chlortetracycline Cholesterol - metabolism Diffusion Fundamental and applied biological sciences. Psychology G(M1) Ganglioside - metabolism Ionophores - pharmacology Lipid Metabolism Male Mammalian male genital system Membrane Microdomains - physiology Morphology. Physiology Phosphorylation - drug effects Proteins - metabolism Sperm Capacitation - physiology Spermatogenesis - physiology Spermatozoa - drug effects Spermatozoa - physiology Sphingomyelin Phosphodiesterase - pharmacology Staining and Labeling Swine Tissue Distribution Tyrosine - metabolism Vertebrates: reproduction
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