Liver Sinusoidal Endothelial Cells Are Insufficient to Activate T Cells

Liver sinusoidal endothelial cells (LSEC) have been reported to express MHC class II, CD80, CD86, and CD11c and effectively stimulate naive T cells. Because dendritic cells (DC) are known to possess these characteristics, we sought to directly compare the phenotype and function of murine LSEC and DC...

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Veröffentlicht in:	The Journal of immunology (1950) 2004-07, Vol.173 (1), p.230-235
Hauptverfasser:	Katz, Steven C, Pillarisetty, Venu G, Bleier, Joshua I, Shah, Alaap B, DeMatteo, Ronald P
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Dendritic Cells - physiology Endothelial Cells - physiology Flow Cytometry Histocompatibility Antigens Class II - biosynthesis Leukocyte Common Antigens - analysis Liver - cytology Liver - immunology Lymphocyte Activation Male Mice Mice, Inbred BALB C Mice, Inbred C57BL T-Lymphocytes - immunology
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