Neoadjuvant imatinib for unresectable gastrointestinal stromal tumor

We have evaluated the feasibility of the use of neoadjuvant imatinib mesylate in the management of unresectable localized gastrointestinal stromal tumors. In a pilot experience, two patients with unresectable gastrointestinal tumors were treated with neoadjuvant imatinib. Their treatment course and...

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Veröffentlicht in:	Anti-cancer drugs 2004-07, Vol.15 (6), p.599-602
Hauptverfasser:	Katz, Daniela, Segal, Amiel, Alberton, Yossef, Jurim, Oded, Reissman, Petachia, Catane, Raphael, Cherny, Nathan I
Format:	Artikel
Sprache:	eng
Schlagworte:	Benzamides Biopsy Clinical Trials, Phase I as Topic Clinical Trials, Phase II as Topic Drug Administration Schedule Follow-Up Studies Gastrectomy Gastrointestinal Neoplasms - diagnosis Gastrointestinal Neoplasms - drug therapy Gastrointestinal Neoplasms - pathology Humans Imatinib Mesylate Intestinal Polyps - diagnosis Intestinal Polyps - pathology Israel Male Middle Aged Neoadjuvant Therapy - methods Neoplasm Invasiveness - diagnostic imaging Piperazines - administration & dosage Piperazines - therapeutic use Postoperative Period Pyrimidines - administration & dosage Pyrimidines - therapeutic use Remission Induction - methods Splenectomy Stromal Cells - drug effects Stromal Cells - pathology Tomography, Spiral Computed Treatment Outcome
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