Three-dimensional microarray platform applied to single nucleotide polymorphism analysis

Bio‐Strand, Inc., has developed a novel DNA microarray platform utilizing a three‐dimensional (3D) DNA format. DNA probes or polymerase chain reaction (PCR) products are spotted onto a thread‐like scaffold, which is then wound onto a cylindrical core. By wrapping the thread around the core, high eff...

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Veröffentlicht in:	Biotechnology and bioengineering 2004-07, Vol.87 (1), p.99-103
Hauptverfasser:	Stimpson, Donald I., Knepper, Sheila M., Shida, Miho, Obata, Kimimichi, Tajima, Hideji
Format:	Artikel
Sprache:	eng
Schlagworte:	3D chip Biological and medical sciences Biotechnology Carbocyanines - chemistry Deoxyribonucleic acid DNA DNA - chemistry DNA chip DNA Probes - chemistry Fundamental and applied biological sciences. Psychology Humans Lasers microarray Nylons - chemistry Oligonucleotide Array Sequence Analysis - methods Polymerase Chain Reaction Polymorphism, Single Nucleotide Sensitivity and Specificity single nucleotide polymorphism (SNP) strand
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