Review of donepezil, rivastigmine, galantamine and memantine for the treatment of dementia in Alzheimer's disease in adults with Down syndrome: implications for the intellectual disability population

The management of dementia in Alzheimer's disease has dramatically changed since the development of anti‐dementia drugs. However, there is limited information available regarding the bio‐medical aspects of the differing drugs; particularly relating to adults with intellectual disability. Indeed...

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Veröffentlicht in:International journal of geriatric psychiatry 2004-06, Vol.19 (6), p.509-515
1. Verfasser: Prasher, V. P.
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container_title International journal of geriatric psychiatry
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description The management of dementia in Alzheimer's disease has dramatically changed since the development of anti‐dementia drugs. However, there is limited information available regarding the bio‐medical aspects of the differing drugs; particularly relating to adults with intellectual disability. Indeed the information available for the intellectual disabled population is limited to adults with Down syndrome. This review highlights the important pharmacological and clinical aspects of donepezil, rivastigmine, galantamine and memantine and supports the view that such drugs play an important part in the management of dementia in adults with intellectual disability. Future clinical and research issues are discussed. Copyright © 2004 John Wiley & Sons, Ltd.
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P.</creatorcontrib><title>Review of donepezil, rivastigmine, galantamine and memantine for the treatment of dementia in Alzheimer's disease in adults with Down syndrome: implications for the intellectual disability population</title><title>International journal of geriatric psychiatry</title><addtitle>Int. J. Geriat. Psychiatry</addtitle><description>The management of dementia in Alzheimer's disease has dramatically changed since the development of anti‐dementia drugs. However, there is limited information available regarding the bio‐medical aspects of the differing drugs; particularly relating to adults with intellectual disability. Indeed the information available for the intellectual disabled population is limited to adults with Down syndrome. 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subjects Alzheimer Disease - drug therapy
Biological and medical sciences
Carbamates - therapeutic use
Cholinesterase Inhibitors - therapeutic use
Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases
dementia
donepezil
Down syndrome
Down Syndrome - complications
galantamine
Galantamine - therapeutic use
Geriatrics
Humans
Indans - therapeutic use
learning disability
Medical sciences
memantine
Memantine - therapeutic use
mental retardation
Neurology
Nootropic Agents - therapeutic use
Phenylcarbamates
Piperidines - therapeutic use
Psychology. Psychoanalysis. Psychiatry
Psychopathology. Psychiatry
Rivastigmine
title Review of donepezil, rivastigmine, galantamine and memantine for the treatment of dementia in Alzheimer's disease in adults with Down syndrome: implications for the intellectual disability population
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