Predictive factors of survival in patients with advanced colorectal cancer: an individual data analysis of 602 patients included in irinotecan phase III trials

Background: The infusional LV5FU2 and Arbeitsgemeinschaft Internische Onkologie (AIO) regimens are used widely in the treatment of advanced colorectal cancer. Irinotecan combined with these regimens increases survival in front-line treatment. Irinotecan also improves survival in second-line treatmen...

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Veröffentlicht in:	Annals of oncology 2004-07, Vol.15 (7), p.1013-1017
Hauptverfasser:	Mitry, E., Douillard, J.-Y., Van Cutsem, E., Cunningham, D., Magherini, E., Mery-Mignard, D., Awad, L., Rougier, P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Antineoplastic agents Antineoplastic Agents, Phytogenic - therapeutic use Biological and medical sciences Camptothecin - analogs & derivatives Camptothecin - therapeutic use chemotherapy colorectal neoplasms Colorectal Neoplasms - drug therapy Colorectal Neoplasms - mortality Drug Therapy, Combination Female Fluorouracil - therapeutic use Humans Irinotecan Male Medical sciences Middle Aged Multivariate Analysis Pharmacology. Drug treatments Prognosis prognostic factors Randomized Controlled Trials as Topic Survival Analysis Survival Rate Treatment Outcome Tumors
Online-Zugang:	Volltext
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