Early T cell response to allografts occurring prior to alloantigen priming up-regulates innate-mediated inflammation and graft necrosis

The early inflammatory response within organ allografts is initiated by ischemia/reperfusion (I/R) and promotes subsequent alloantigen-primed T cell recruitment into and rejection of the graft. Polymorphonuclear leukocyte (PMN)-mediated tissue damage is a primary component of the early inflammation...

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Veröffentlicht in:The American journal of pathology 2004-07, Vol.165 (1), p.147-157
Hauptverfasser: El-Sawy, Tarek, Miura, Masayoshi, Fairchild, Robert
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Sprache:eng
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