Determination of the rat tissue partitioning of endotoxin in vitro for physiologically-based pharmacokinetic (PBPK) modeling

The biosynthetically double‐labeled lipopolysaccharide (LPS), containing 3H‐labeled on the fatty acyl‐chains and 14C‐labeled on the glucosamine of Salmonella enterica serotype typhimurium, was isolated from bacteria grown in proteose peptone‐beef extract (PPBE) medium in the presence of labeled prec...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of applied toxicology 2004-05, Vol.24 (3), p.177-181
Hauptverfasser:	Ross, Ivan A., Sapienza, Philip P., Hanes, Darcy E., Johnson, Widmark, Kim, Chung S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences endotoxin Endotoxins - pharmacokinetics Food industries Food microbiology Food toxicology Fundamental and applied biological sciences. Psychology Lipopolysaccharides - isolation & purification Medical sciences Models, Biological partition coefﬁcients PBPK modeling Rats Rats, Sprague-Dawley Salmonella enterica Salmonella typhimurium Tissue Distribution Toxicology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!