Extracellular HMGB1 as a proinflammatory cytokine
High mobility group box-1 protein (HMGB1, formerly known as HMG-1), a highly conserved ubiquitous protein, has been for a long time described as a nuclear DNA-binding protein involved in nucleosome stabilization and gene transcription. Recent discoveries indicate that HMGB1 is released from activate...
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Veröffentlicht in: | Journal of interferon & cytokine research 2004-06, Vol.24 (6), p.329-333 |
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Format: | Artikel |
Sprache: | eng |
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