Effects of Huangqi (Hex) on inducing cell differentiation and cell death in K562 and HEL cells

Huangqi (Astragalus membranaceus), a traditional Chinese medicine, has been used to ameliorate side effects of cancer chemotherapy in China. However, little is known about its molecular mechanisms. Here we show that induction of K562 or HEL cells with 1.5 mg/ml of Huangqi (Hex) (Components extracted...

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Veröffentlicht in:	Acta biochimica et biophysica Sinica 2004-03, Vol.36 (3), p.211-217
Hauptverfasser:	Cheng, Xiao-Dong, Hou, Chun-Hui, Zhang, Xue-Jun, Xie, Heng-Yue, Zhou, Wei-Ying, Yang, Lei, Zhang, Shu-Bing, Qian, Ruo-Lan
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylcholinesterase - metabolism Apoptosis - drug effects Astragalus Plant Caspase 3 Caspases - metabolism Cell Differentiation - drug effects Cell Line, Tumor Dose-Response Relationship, Drug Drugs, Chinese Herbal - pharmacology Enzyme Activation - drug effects Gene Expression Regulation, Neoplastic Globins - metabolism Humans K562 Cells Leukemia, Erythroblastic, Acute - pathology Leukemia, Erythroblastic, Acute - physiopathology
Online-Zugang:	Volltext
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