Provocative and inhibitory effects of a video‐EEG neuropsychologic protocol in juvenile myoclonic epilepsy
Summary Purpose: Studies suggest that higher cognitive functions could precipitate seizures in juvenile myoclonic epilepsy (JME). The present study aimed to analyze the effects of higher mental activity on epileptiform discharges and seizures in patients with JME and compare them to those of habitu...
Gespeichert in:
| Veröffentlicht in: | Epilepsia (Copenhagen) 2009-11, Vol.50 (11), p.2446-2455 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 2455 |
|---|---|
| container_issue | 11 |
| container_start_page | 2446 |
| container_title | Epilepsia (Copenhagen) |
| container_volume | 50 |
| creator | Guaranha, Mirian Salvadori Bittar Da Silva Sousa, Patrícia De Araújo‐Filho, Gerardo Maria Lin, Katia Guilhoto, Laura Maria Figueiredo Ferreira Caboclo, Luís Otávio Sales Ferreira Yacubian, Elza Márcia Targas |
| description | Summary
Purpose: Studies suggest that higher cognitive functions could precipitate seizures in juvenile myoclonic epilepsy (JME). The present study aimed to analyze the effects of higher mental activity on epileptiform discharges and seizures in patients with JME and compare them to those of habitual methods of activation.
Methods: Seventy‐six patients with JME (41 female) underwent a video‐EEG (electroencephalography) neuropsychologic protocol (VNPP) and habitual methods of activation for 4–6 h.
Results: Twenty‐nine of the 76 (38.2%) presented provocative effect, and inhibition was seen in 28 of 31 (90.3%). A mixed effect was observed in 11 (35.5%), and 30 patients (39.5%) suffered no effect of VNPP. Action‐programming tasks were more effective than thinking in provoking epileptiform discharges (23.7% and 11.0% of patients, respectively, p = 0.03). Inhibitory effect was observed equally in the various categories of tasks, except in mental calculation, which had a higher inhibitory rate. Habitual methods of activation were more effective than VNPP in provoking discharges. Anxiety disorders were diagnosed in 24 of 58 patients (41.4%); anxious patients had greater discharge indexes and no significant inhibitory effect on VNPP.
Discussion: Praxis exerted the most remarkable provocative effect, in accordance with the motor circuitry hyperexcitability hypothesis in JME. Inhibitory effect, which had no such task specificity, might be mediated by a widespread cortical–thalamic pathway, possibly involving the parietal cortex. The frequent inhibitory effect found under cortical activation conditions, influenced by the presence of anxiety, supports nonpharmacologic therapeutic interventions in JME. |
| doi_str_mv | 10.1111/j.1528-1167.2009.02126.x |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_66639603</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>66639603</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4786-81c2c1f94337d5f45c097414b30905a832ef1223611871eaaa35d3a6f16db33f3</originalsourceid><addsrcrecordid>eNqNkcFu3CAQhlHVqtmkfYWKS3qzw4AN9qGHKNomkSIlh_aMWAwNK9Zswd6sb32EPmOfJDi7So8tF0Dzzcyv_0cIAykhn4t1CTVtCgAuSkpIWxIKlJf7N2jxWniLFoQAK9q6ISfoNKU1IURwwd6jE2irmgmoFsg_xLALWg1uZ7DqO-z6R7dyQ4gTNtYaPSQcLFZ45zoT_vz6vVxe496MMWzTpB-DDz-cxtsYhqCDz914Pe5M77zBmyloH_pcNtv8z_wH9M4qn8zH432Gvn9dfru6Ke7ur2-vLu8KXYmGFw1oqsG2FWOiq21Va9KKCqoVIy2pVcOosUAp4wCNAKOUYnXHFLfAuxVjlp2hz4e5WdfP0aRBblzSxnvVmzAmyTlnLSfsnyAFEPOiDDYHUMeQUjRWbqPbqDhJIHKORK7l7LycnZdzJPIlErnPrZ-OO8bVxnR_G48ZZOD8CKiklbdR9dqlV45S0jIQs9gvB-4puzn9twC5fLidX-wZeXGonA</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>21172236</pqid></control><display><type>article</type><title>Provocative and inhibitory effects of a video‐EEG neuropsychologic protocol in juvenile myoclonic epilepsy</title><source>MEDLINE</source><source>IngentaConnect Open Access Journals</source><source>Wiley Online Library Journals Frontfile Complete</source><source>Wiley Online Library Free Content</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>Alma/SFX Local Collection</source><creator>Guaranha, Mirian Salvadori Bittar ; Da Silva Sousa, Patrícia ; De Araújo‐Filho, Gerardo Maria ; Lin, Katia ; Guilhoto, Laura Maria Figueiredo Ferreira ; Caboclo, Luís Otávio Sales Ferreira ; Yacubian, Elza Márcia Targas</creator><creatorcontrib>Guaranha, Mirian Salvadori Bittar ; Da Silva Sousa, Patrícia ; De Araújo‐Filho, Gerardo Maria ; Lin, Katia ; Guilhoto, Laura Maria Figueiredo Ferreira ; Caboclo, Luís Otávio Sales Ferreira ; Yacubian, Elza Márcia Targas</creatorcontrib><description>Summary
Purpose: Studies suggest that higher cognitive functions could precipitate seizures in juvenile myoclonic epilepsy (JME). The present study aimed to analyze the effects of higher mental activity on epileptiform discharges and seizures in patients with JME and compare them to those of habitual methods of activation.
Methods: Seventy‐six patients with JME (41 female) underwent a video‐EEG (electroencephalography) neuropsychologic protocol (VNPP) and habitual methods of activation for 4–6 h.
Results: Twenty‐nine of the 76 (38.2%) presented provocative effect, and inhibition was seen in 28 of 31 (90.3%). A mixed effect was observed in 11 (35.5%), and 30 patients (39.5%) suffered no effect of VNPP. Action‐programming tasks were more effective than thinking in provoking epileptiform discharges (23.7% and 11.0% of patients, respectively, p = 0.03). Inhibitory effect was observed equally in the various categories of tasks, except in mental calculation, which had a higher inhibitory rate. Habitual methods of activation were more effective than VNPP in provoking discharges. Anxiety disorders were diagnosed in 24 of 58 patients (41.4%); anxious patients had greater discharge indexes and no significant inhibitory effect on VNPP.
Discussion: Praxis exerted the most remarkable provocative effect, in accordance with the motor circuitry hyperexcitability hypothesis in JME. Inhibitory effect, which had no such task specificity, might be mediated by a widespread cortical–thalamic pathway, possibly involving the parietal cortex. The frequent inhibitory effect found under cortical activation conditions, influenced by the presence of anxiety, supports nonpharmacologic therapeutic interventions in JME.</description><identifier>ISSN: 0013-9580</identifier><identifier>EISSN: 1528-1167</identifier><identifier>DOI: 10.1111/j.1528-1167.2009.02126.x</identifier><identifier>PMID: 19453714</identifier><identifier>CODEN: EPILAK</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Publishing Ltd</publisher><subject>Activation methods ; Adolescent ; Adult ; Anticonvulsants. Antiepileptics. Antiparkinson agents ; Biological and medical sciences ; Cerebral Cortex - physiopathology ; Child ; Electroencephalography - methods ; Electroencephalography - statistics & numerical data ; Epilepsy, Reflex - physiopathology ; Female ; Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy ; Higher Nervous Activity - physiology ; Humans ; Idiopathic generalized epilepsy ; Male ; Medical sciences ; Middle Aged ; Myoclonic Epilepsy, Juvenile - diagnosis ; Myoclonic Epilepsy, Juvenile - drug therapy ; Myoclonic Epilepsy, Juvenile - physiopathology ; Nervous system (semeiology, syndromes) ; Neural Inhibition - physiology ; Neural Pathways - physiopathology ; Neurology ; Neuropharmacology ; Neuropsychology ; Parietal Lobe - physiopathology ; Pharmacology. Drug treatments ; Photic Stimulation ; Precipitant factors ; Precipitating Factors ; Reflex epilepsy ; Task Performance and Analysis ; Thalamus - physiopathology ; Videotape Recording</subject><ispartof>Epilepsia (Copenhagen), 2009-11, Vol.50 (11), p.2446-2455</ispartof><rights>Wiley Periodicals, Inc. © 2009 International League Against Epilepsy</rights><rights>2009 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4786-81c2c1f94337d5f45c097414b30905a832ef1223611871eaaa35d3a6f16db33f3</citedby><cites>FETCH-LOGICAL-c4786-81c2c1f94337d5f45c097414b30905a832ef1223611871eaaa35d3a6f16db33f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fj.1528-1167.2009.02126.x$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fj.1528-1167.2009.02126.x$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,1427,27901,27902,45550,45551,46384,46808</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=22093173$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19453714$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Guaranha, Mirian Salvadori Bittar</creatorcontrib><creatorcontrib>Da Silva Sousa, Patrícia</creatorcontrib><creatorcontrib>De Araújo‐Filho, Gerardo Maria</creatorcontrib><creatorcontrib>Lin, Katia</creatorcontrib><creatorcontrib>Guilhoto, Laura Maria Figueiredo Ferreira</creatorcontrib><creatorcontrib>Caboclo, Luís Otávio Sales Ferreira</creatorcontrib><creatorcontrib>Yacubian, Elza Márcia Targas</creatorcontrib><title>Provocative and inhibitory effects of a video‐EEG neuropsychologic protocol in juvenile myoclonic epilepsy</title><title>Epilepsia (Copenhagen)</title><addtitle>Epilepsia</addtitle><description>Summary
Purpose: Studies suggest that higher cognitive functions could precipitate seizures in juvenile myoclonic epilepsy (JME). The present study aimed to analyze the effects of higher mental activity on epileptiform discharges and seizures in patients with JME and compare them to those of habitual methods of activation.
Methods: Seventy‐six patients with JME (41 female) underwent a video‐EEG (electroencephalography) neuropsychologic protocol (VNPP) and habitual methods of activation for 4–6 h.
Results: Twenty‐nine of the 76 (38.2%) presented provocative effect, and inhibition was seen in 28 of 31 (90.3%). A mixed effect was observed in 11 (35.5%), and 30 patients (39.5%) suffered no effect of VNPP. Action‐programming tasks were more effective than thinking in provoking epileptiform discharges (23.7% and 11.0% of patients, respectively, p = 0.03). Inhibitory effect was observed equally in the various categories of tasks, except in mental calculation, which had a higher inhibitory rate. Habitual methods of activation were more effective than VNPP in provoking discharges. Anxiety disorders were diagnosed in 24 of 58 patients (41.4%); anxious patients had greater discharge indexes and no significant inhibitory effect on VNPP.
Discussion: Praxis exerted the most remarkable provocative effect, in accordance with the motor circuitry hyperexcitability hypothesis in JME. Inhibitory effect, which had no such task specificity, might be mediated by a widespread cortical–thalamic pathway, possibly involving the parietal cortex. The frequent inhibitory effect found under cortical activation conditions, influenced by the presence of anxiety, supports nonpharmacologic therapeutic interventions in JME.</description><subject>Activation methods</subject><subject>Adolescent</subject><subject>Adult</subject><subject>Anticonvulsants. Antiepileptics. Antiparkinson agents</subject><subject>Biological and medical sciences</subject><subject>Cerebral Cortex - physiopathology</subject><subject>Child</subject><subject>Electroencephalography - methods</subject><subject>Electroencephalography - statistics & numerical data</subject><subject>Epilepsy, Reflex - physiopathology</subject><subject>Female</subject><subject>Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy</subject><subject>Higher Nervous Activity - physiology</subject><subject>Humans</subject><subject>Idiopathic generalized epilepsy</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Myoclonic Epilepsy, Juvenile - diagnosis</subject><subject>Myoclonic Epilepsy, Juvenile - drug therapy</subject><subject>Myoclonic Epilepsy, Juvenile - physiopathology</subject><subject>Nervous system (semeiology, syndromes)</subject><subject>Neural Inhibition - physiology</subject><subject>Neural Pathways - physiopathology</subject><subject>Neurology</subject><subject>Neuropharmacology</subject><subject>Neuropsychology</subject><subject>Parietal Lobe - physiopathology</subject><subject>Pharmacology. Drug treatments</subject><subject>Photic Stimulation</subject><subject>Precipitant factors</subject><subject>Precipitating Factors</subject><subject>Reflex epilepsy</subject><subject>Task Performance and Analysis</subject><subject>Thalamus - physiopathology</subject><subject>Videotape Recording</subject><issn>0013-9580</issn><issn>1528-1167</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkcFu3CAQhlHVqtmkfYWKS3qzw4AN9qGHKNomkSIlh_aMWAwNK9Zswd6sb32EPmOfJDi7So8tF0Dzzcyv_0cIAykhn4t1CTVtCgAuSkpIWxIKlJf7N2jxWniLFoQAK9q6ISfoNKU1IURwwd6jE2irmgmoFsg_xLALWg1uZ7DqO-z6R7dyQ4gTNtYaPSQcLFZ45zoT_vz6vVxe496MMWzTpB-DDz-cxtsYhqCDz914Pe5M77zBmyloH_pcNtv8z_wH9M4qn8zH432Gvn9dfru6Ke7ur2-vLu8KXYmGFw1oqsG2FWOiq21Va9KKCqoVIy2pVcOosUAp4wCNAKOUYnXHFLfAuxVjlp2hz4e5WdfP0aRBblzSxnvVmzAmyTlnLSfsnyAFEPOiDDYHUMeQUjRWbqPbqDhJIHKORK7l7LycnZdzJPIlErnPrZ-OO8bVxnR_G48ZZOD8CKiklbdR9dqlV45S0jIQs9gvB-4puzn9twC5fLidX-wZeXGonA</recordid><startdate>200911</startdate><enddate>200911</enddate><creator>Guaranha, Mirian Salvadori Bittar</creator><creator>Da Silva Sousa, Patrícia</creator><creator>De Araújo‐Filho, Gerardo Maria</creator><creator>Lin, Katia</creator><creator>Guilhoto, Laura Maria Figueiredo Ferreira</creator><creator>Caboclo, Luís Otávio Sales Ferreira</creator><creator>Yacubian, Elza Márcia Targas</creator><general>Blackwell Publishing Ltd</general><general>Wiley-Blackwell</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TK</scope><scope>7X8</scope></search><sort><creationdate>200911</creationdate><title>Provocative and inhibitory effects of a video‐EEG neuropsychologic protocol in juvenile myoclonic epilepsy</title><author>Guaranha, Mirian Salvadori Bittar ; Da Silva Sousa, Patrícia ; De Araújo‐Filho, Gerardo Maria ; Lin, Katia ; Guilhoto, Laura Maria Figueiredo Ferreira ; Caboclo, Luís Otávio Sales Ferreira ; Yacubian, Elza Márcia Targas</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4786-81c2c1f94337d5f45c097414b30905a832ef1223611871eaaa35d3a6f16db33f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>Activation methods</topic><topic>Adolescent</topic><topic>Adult</topic><topic>Anticonvulsants. Antiepileptics. Antiparkinson agents</topic><topic>Biological and medical sciences</topic><topic>Cerebral Cortex - physiopathology</topic><topic>Child</topic><topic>Electroencephalography - methods</topic><topic>Electroencephalography - statistics & numerical data</topic><topic>Epilepsy, Reflex - physiopathology</topic><topic>Female</topic><topic>Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy</topic><topic>Higher Nervous Activity - physiology</topic><topic>Humans</topic><topic>Idiopathic generalized epilepsy</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Myoclonic Epilepsy, Juvenile - diagnosis</topic><topic>Myoclonic Epilepsy, Juvenile - drug therapy</topic><topic>Myoclonic Epilepsy, Juvenile - physiopathology</topic><topic>Nervous system (semeiology, syndromes)</topic><topic>Neural Inhibition - physiology</topic><topic>Neural Pathways - physiopathology</topic><topic>Neurology</topic><topic>Neuropharmacology</topic><topic>Neuropsychology</topic><topic>Parietal Lobe - physiopathology</topic><topic>Pharmacology. Drug treatments</topic><topic>Photic Stimulation</topic><topic>Precipitant factors</topic><topic>Precipitating Factors</topic><topic>Reflex epilepsy</topic><topic>Task Performance and Analysis</topic><topic>Thalamus - physiopathology</topic><topic>Videotape Recording</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Guaranha, Mirian Salvadori Bittar</creatorcontrib><creatorcontrib>Da Silva Sousa, Patrícia</creatorcontrib><creatorcontrib>De Araújo‐Filho, Gerardo Maria</creatorcontrib><creatorcontrib>Lin, Katia</creatorcontrib><creatorcontrib>Guilhoto, Laura Maria Figueiredo Ferreira</creatorcontrib><creatorcontrib>Caboclo, Luís Otávio Sales Ferreira</creatorcontrib><creatorcontrib>Yacubian, Elza Márcia Targas</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Neurosciences Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Epilepsia (Copenhagen)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Guaranha, Mirian Salvadori Bittar</au><au>Da Silva Sousa, Patrícia</au><au>De Araújo‐Filho, Gerardo Maria</au><au>Lin, Katia</au><au>Guilhoto, Laura Maria Figueiredo Ferreira</au><au>Caboclo, Luís Otávio Sales Ferreira</au><au>Yacubian, Elza Márcia Targas</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Provocative and inhibitory effects of a video‐EEG neuropsychologic protocol in juvenile myoclonic epilepsy</atitle><jtitle>Epilepsia (Copenhagen)</jtitle><addtitle>Epilepsia</addtitle><date>2009-11</date><risdate>2009</risdate><volume>50</volume><issue>11</issue><spage>2446</spage><epage>2455</epage><pages>2446-2455</pages><issn>0013-9580</issn><eissn>1528-1167</eissn><coden>EPILAK</coden><abstract>Summary
Purpose: Studies suggest that higher cognitive functions could precipitate seizures in juvenile myoclonic epilepsy (JME). The present study aimed to analyze the effects of higher mental activity on epileptiform discharges and seizures in patients with JME and compare them to those of habitual methods of activation.
Methods: Seventy‐six patients with JME (41 female) underwent a video‐EEG (electroencephalography) neuropsychologic protocol (VNPP) and habitual methods of activation for 4–6 h.
Results: Twenty‐nine of the 76 (38.2%) presented provocative effect, and inhibition was seen in 28 of 31 (90.3%). A mixed effect was observed in 11 (35.5%), and 30 patients (39.5%) suffered no effect of VNPP. Action‐programming tasks were more effective than thinking in provoking epileptiform discharges (23.7% and 11.0% of patients, respectively, p = 0.03). Inhibitory effect was observed equally in the various categories of tasks, except in mental calculation, which had a higher inhibitory rate. Habitual methods of activation were more effective than VNPP in provoking discharges. Anxiety disorders were diagnosed in 24 of 58 patients (41.4%); anxious patients had greater discharge indexes and no significant inhibitory effect on VNPP.
Discussion: Praxis exerted the most remarkable provocative effect, in accordance with the motor circuitry hyperexcitability hypothesis in JME. Inhibitory effect, which had no such task specificity, might be mediated by a widespread cortical–thalamic pathway, possibly involving the parietal cortex. The frequent inhibitory effect found under cortical activation conditions, influenced by the presence of anxiety, supports nonpharmacologic therapeutic interventions in JME.</abstract><cop>Oxford, UK</cop><pub>Blackwell Publishing Ltd</pub><pmid>19453714</pmid><doi>10.1111/j.1528-1167.2009.02126.x</doi><tpages>10</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0013-9580 |
| ispartof | Epilepsia (Copenhagen), 2009-11, Vol.50 (11), p.2446-2455 |
| issn | 0013-9580 1528-1167 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_66639603 |
| source | MEDLINE; IngentaConnect Open Access Journals; Wiley Online Library Journals Frontfile Complete; Wiley Online Library Free Content; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection |
| subjects | Activation methods Adolescent Adult Anticonvulsants. Antiepileptics. Antiparkinson agents Biological and medical sciences Cerebral Cortex - physiopathology Child Electroencephalography - methods Electroencephalography - statistics & numerical data Epilepsy, Reflex - physiopathology Female Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy Higher Nervous Activity - physiology Humans Idiopathic generalized epilepsy Male Medical sciences Middle Aged Myoclonic Epilepsy, Juvenile - diagnosis Myoclonic Epilepsy, Juvenile - drug therapy Myoclonic Epilepsy, Juvenile - physiopathology Nervous system (semeiology, syndromes) Neural Inhibition - physiology Neural Pathways - physiopathology Neurology Neuropharmacology Neuropsychology Parietal Lobe - physiopathology Pharmacology. Drug treatments Photic Stimulation Precipitant factors Precipitating Factors Reflex epilepsy Task Performance and Analysis Thalamus - physiopathology Videotape Recording |
| title | Provocative and inhibitory effects of a video‐EEG neuropsychologic protocol in juvenile myoclonic epilepsy |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-11T11%3A11%3A31IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Provocative%20and%20inhibitory%20effects%20of%20a%20video%E2%80%90EEG%20neuropsychologic%20protocol%20in%20juvenile%20myoclonic%20epilepsy&rft.jtitle=Epilepsia%20(Copenhagen)&rft.au=Guaranha,%20Mirian%20Salvadori%20Bittar&rft.date=2009-11&rft.volume=50&rft.issue=11&rft.spage=2446&rft.epage=2455&rft.pages=2446-2455&rft.issn=0013-9580&rft.eissn=1528-1167&rft.coden=EPILAK&rft_id=info:doi/10.1111/j.1528-1167.2009.02126.x&rft_dat=%3Cproquest_cross%3E66639603%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=21172236&rft_id=info:pmid/19453714&rfr_iscdi=true |