Acupuncture for the treatment of cocaine addiction investigation of a needle puncture control
We conducted a 6-week, single-blind study of acupuncture for cocaine dependence in methadone-maintained patients ( N = 40) for the purpose of identifying an appropriate needle puncture control for use in future large-scale clinical trials. Patients were randomly assigned to receive daily acupuncture...
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| Veröffentlicht in: | Journal of substance abuse treatment 1995-05, Vol.12 (3), p.195-205 |
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| container_title | Journal of substance abuse treatment |
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| creator | Kelly Avants, S. Margolin, Arthur Chang, Patrick Kosten, Thomas R. Birch, Stephen |
| description | We conducted a 6-week, single-blind study of acupuncture for cocaine dependence in methadone-maintained patients (
N = 40) for the purpose of identifying an appropriate needle puncture control for use in future large-scale clinical trials. Patients were randomly assigned to receive daily acupuncture in three auricular sites plus one body site (LI-4), or in control sites within 2–3 mm of the four active sites. Overall, there was a positive response to treatment on a variety of drugrelated and psychosocial measures. Cocaine use decreased significantly for patients in both needle puncture groups. The only statistically significant difference between the two types of needle puncture was on ratings of craving. Subjects rated each type of needle puncture as equally credible and perceived no significant differences on the acute effects of the two types of needle insertions. Power calculations based on these findings suggest that very large sample sizes would be required to detect treatment differences between this control condition and active acupuncture. Alternative controls are suggested, and the challenges inherent in implementing controlled clinical trials of acupuncture are discussed. |
| doi_str_mv | 10.1016/0740-5472(95)00014-V |
| format | Article |
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N = 40) for the purpose of identifying an appropriate needle puncture control for use in future large-scale clinical trials. Patients were randomly assigned to receive daily acupuncture in three auricular sites plus one body site (LI-4), or in control sites within 2–3 mm of the four active sites. Overall, there was a positive response to treatment on a variety of drugrelated and psychosocial measures. Cocaine use decreased significantly for patients in both needle puncture groups. The only statistically significant difference between the two types of needle puncture was on ratings of craving. Subjects rated each type of needle puncture as equally credible and perceived no significant differences on the acute effects of the two types of needle insertions. Power calculations based on these findings suggest that very large sample sizes would be required to detect treatment differences between this control condition and active acupuncture. Alternative controls are suggested, and the challenges inherent in implementing controlled clinical trials of acupuncture are discussed.</description><subject>Acupuncture</subject><subject>Acupuncture Points</subject><subject>Acupuncture Therapy</subject><subject>Adult</subject><subject>Biological and medical sciences</subject><subject>Cocaine</subject><subject>Combined Modality Therapy</subject><subject>Comorbidity</subject><subject>Desintoxication. Drug withdrawal</subject><subject>Detoxification</subject><subject>Drug Addiction</subject><subject>Ear, External</subject><subject>Female</subject><subject>HIV Seropositivity - transmission</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>methadone</subject><subject>Methadone - therapeutic use</subject><subject>methodology</subject><subject>Middle Aged</subject><subject>Opioid-Related Disorders - rehabilitation</subject><subject>Psychology. Psychoanalysis. Psychiatry</subject><subject>Psychopathology. Psychiatry</subject><subject>Single-Blind Method</subject><subject>Social research</subject><subject>substance abuse</subject><subject>Substance abuse treatment</subject><subject>Substance Abuse, Intravenous - rehabilitation</subject><subject>Substance Withdrawal Syndrome - prevention & control</subject><subject>Substance-Related Disorders - rehabilitation</subject><subject>Traditional Medicine</subject><subject>Treatment Outcome</subject><subject>Treatment Outcomes</subject><subject>Treatments</subject><issn>0740-5472</issn><issn>1873-6483</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1995</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>7QJ</sourceid><sourceid>BHHNA</sourceid><recordid>eNp9kVuLFDEQhYMo6zj6DxQaEVkfWnNP98vCsniDBV903yTkUq1ZepIxSS_4703vDPPgw0KgCOerouochF4S_J5gIj9gxXEvuKLno3iHMSa8v3mENmRQrJd8YI_R5oQ8Rc9KuW0QpXg4Q2eKN4WqDfp56Zb9El1dMnRTyl39DV3NYOoOYu3S1LnkTIjQGe-DqyHFLsQ7KDX8Mve_hpguAvgZutMkl2LNaX6OnkxmLvDiWLfox6eP36--9NffPn-9urzunaCs9mrwZDBDK4JJNVqlDJFUCuwHQUdMBmqttxyPWCgGwhrPsZ2EtYIIbibMtujtYe4-pz9LW07vQnEwzyZCWoqWREjOqGrg-YMgUZKo5hpf0df_obdpybGdoSlRjJP1bRE_QC6nUjJMep_DzuS_mmC9pqTXCPQagR6Fvk9J37S2V8fZi92BPzUdY2n6m6NuijPzlE10oZwwJptteGzYxQGD5u1dgKyLCxAd-JDBVe1TeHiPf93CrK0</recordid><startdate>19950501</startdate><enddate>19950501</enddate><creator>Kelly Avants, S.</creator><creator>Margolin, Arthur</creator><creator>Chang, Patrick</creator><creator>Kosten, Thomas R.</creator><creator>Birch, Stephen</creator><general>Elsevier Inc</general><general>Elsevier Science</general><general>Elsevier Limited</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QJ</scope><scope>K7.</scope><scope>K9.</scope><scope>7U3</scope><scope>BHHNA</scope></search><sort><creationdate>19950501</creationdate><title>Acupuncture for the treatment of cocaine addiction investigation of a needle puncture control</title><author>Kelly Avants, S. ; Margolin, Arthur ; Chang, Patrick ; Kosten, Thomas R. ; Birch, Stephen</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c523t-78d18a878d53679b77a162650d85290182bbdb4090573e5bad40bf5bb5154af03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1995</creationdate><topic>Acupuncture</topic><topic>Acupuncture Points</topic><topic>Acupuncture Therapy</topic><topic>Adult</topic><topic>Biological and medical sciences</topic><topic>Cocaine</topic><topic>Combined Modality Therapy</topic><topic>Comorbidity</topic><topic>Desintoxication. 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Psychiatry</topic><topic>Single-Blind Method</topic><topic>Social research</topic><topic>substance abuse</topic><topic>Substance abuse treatment</topic><topic>Substance Abuse, Intravenous - rehabilitation</topic><topic>Substance Withdrawal Syndrome - prevention & control</topic><topic>Substance-Related Disorders - rehabilitation</topic><topic>Traditional Medicine</topic><topic>Treatment Outcome</topic><topic>Treatment Outcomes</topic><topic>Treatments</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kelly Avants, S.</creatorcontrib><creatorcontrib>Margolin, Arthur</creatorcontrib><creatorcontrib>Chang, Patrick</creatorcontrib><creatorcontrib>Kosten, Thomas R.</creatorcontrib><creatorcontrib>Birch, Stephen</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Applied Social Sciences Index & Abstracts (ASSIA)</collection><collection>ProQuest Criminal Justice (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Social Services Abstracts</collection><collection>Sociological Abstracts</collection><jtitle>Journal of substance abuse treatment</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kelly Avants, S.</au><au>Margolin, Arthur</au><au>Chang, Patrick</au><au>Kosten, Thomas R.</au><au>Birch, Stephen</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Acupuncture for the treatment of cocaine addiction investigation of a needle puncture control</atitle><jtitle>Journal of substance abuse treatment</jtitle><addtitle>J Subst Abuse Treat</addtitle><date>1995-05-01</date><risdate>1995</risdate><volume>12</volume><issue>3</issue><spage>195</spage><epage>205</epage><pages>195-205</pages><issn>0740-5472</issn><eissn>1873-6483</eissn><coden>JSATEG</coden><abstract>We conducted a 6-week, single-blind study of acupuncture for cocaine dependence in methadone-maintained patients (
N = 40) for the purpose of identifying an appropriate needle puncture control for use in future large-scale clinical trials. Patients were randomly assigned to receive daily acupuncture in three auricular sites plus one body site (LI-4), or in control sites within 2–3 mm of the four active sites. Overall, there was a positive response to treatment on a variety of drugrelated and psychosocial measures. Cocaine use decreased significantly for patients in both needle puncture groups. The only statistically significant difference between the two types of needle puncture was on ratings of craving. Subjects rated each type of needle puncture as equally credible and perceived no significant differences on the acute effects of the two types of needle insertions. Power calculations based on these findings suggest that very large sample sizes would be required to detect treatment differences between this control condition and active acupuncture. Alternative controls are suggested, and the challenges inherent in implementing controlled clinical trials of acupuncture are discussed.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>7474027</pmid><doi>10.1016/0740-5472(95)00014-V</doi><tpages>11</tpages><oa>free_for_read</oa></addata></record> |
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| source | MEDLINE; Sociological Abstracts; Applied Social Sciences Index & Abstracts (ASSIA); Access via ScienceDirect (Elsevier) |
| subjects | Acupuncture Acupuncture Points Acupuncture Therapy Adult Biological and medical sciences Cocaine Combined Modality Therapy Comorbidity Desintoxication. Drug withdrawal Detoxification Drug Addiction Ear, External Female HIV Seropositivity - transmission Humans Male Medical sciences methadone Methadone - therapeutic use methodology Middle Aged Opioid-Related Disorders - rehabilitation Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Single-Blind Method Social research substance abuse Substance abuse treatment Substance Abuse, Intravenous - rehabilitation Substance Withdrawal Syndrome - prevention & control Substance-Related Disorders - rehabilitation Traditional Medicine Treatment Outcome Treatment Outcomes Treatments |
| title | Acupuncture for the treatment of cocaine addiction investigation of a needle puncture control |
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