Effect of vitamin A supplementation on morbidity due to Plasmodium falciparum in young children in Papua New Guinea: a randomised trial
Notes that many individuals at risk of malaria also have micronutrient deficiencies that may hamper protective immunity. Investigates the effect of vitamin A supplementation on malaria morbidity, and finds that it may be an effective low-cost strategy to lower morbidity in young children. Findings s...
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| Veröffentlicht in: | The Lancet (British edition) 1999-07, Vol.17, p.203-209 |
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| container_title | The Lancet (British edition) |
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| creator | Shankar, A H Genton, B Semba, R D Baisor, M Paino, J Tamja, S Adiguma, T Wu, L Rare, L Tielsch, J M Alpers, M P West, K P |
| description | Notes that many individuals at risk of malaria also have micronutrient deficiencies that may hamper protective immunity. Investigates the effect of vitamin A supplementation on malaria morbidity, and finds that it may be an effective low-cost strategy to lower morbidity in young children. Findings suggest that clinical episodes, spleen enlargement, and parasite density are influenced by different immunological mechanisms from infection and anaemia. (Original abstract - amended) |
| format | Article |
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Investigates the effect of vitamin A supplementation on malaria morbidity, and finds that it may be an effective low-cost strategy to lower morbidity in young children. Findings suggest that clinical episodes, spleen enlargement, and parasite density are influenced by different immunological mechanisms from infection and anaemia. 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Investigates the effect of vitamin A supplementation on malaria morbidity, and finds that it may be an effective low-cost strategy to lower morbidity in young children. Findings suggest that clinical episodes, spleen enlargement, and parasite density are influenced by different immunological mechanisms from infection and anaemia. (Original abstract - amended)</description><subject>Double blind randomized controlled trials</subject><subject>Malaria</subject><subject>Papua New Guinea</subject><subject>Prevention</subject><subject>Vitamin A supplement</subject><subject>Young children</subject><issn>0140-6736</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1999</creationdate><recordtype>article</recordtype><sourceid>7QJ</sourceid><recordid>eNqNT8tqAkEQnINCjPoPffImjOjuQm5BNDkFD96l3enVDjPT4zwMfkF-OxPIBwQKqiiqCmqkJnq10cu2W7dP6jmlT631ptXNRH3vhoH6DDLAnTM69vAKqYRgyZHPmFk8VDiJZzacH2AKQRY4WExODBcHA9qeA8Yqa_0hxV-gv7I1kfyvc8BQED7oC94Ke8IXQIjojThOZCBHRjtT4zqTaP7HU7XY747b92WIciuU8qmGe7IWPUlJp6brmvpAr_8d_AEdBVXX</recordid><startdate>19990701</startdate><enddate>19990701</enddate><creator>Shankar, A H</creator><creator>Genton, B</creator><creator>Semba, R D</creator><creator>Baisor, M</creator><creator>Paino, J</creator><creator>Tamja, S</creator><creator>Adiguma, T</creator><creator>Wu, L</creator><creator>Rare, L</creator><creator>Tielsch, J M</creator><creator>Alpers, M P</creator><creator>West, K P</creator><scope>7QJ</scope></search><sort><creationdate>19990701</creationdate><title>Effect of vitamin A supplementation on morbidity due to Plasmodium falciparum in young children in Papua New Guinea: a randomised trial</title><author>Shankar, A H ; Genton, B ; Semba, R D ; Baisor, M ; Paino, J ; Tamja, S ; Adiguma, T ; Wu, L ; Rare, L ; Tielsch, J M ; Alpers, M P ; West, K P</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-proquest_miscellaneous_577546003</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1999</creationdate><topic>Double blind randomized controlled trials</topic><topic>Malaria</topic><topic>Papua New Guinea</topic><topic>Prevention</topic><topic>Vitamin A supplement</topic><topic>Young children</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Shankar, A H</creatorcontrib><creatorcontrib>Genton, B</creatorcontrib><creatorcontrib>Semba, R D</creatorcontrib><creatorcontrib>Baisor, M</creatorcontrib><creatorcontrib>Paino, J</creatorcontrib><creatorcontrib>Tamja, S</creatorcontrib><creatorcontrib>Adiguma, T</creatorcontrib><creatorcontrib>Wu, L</creatorcontrib><creatorcontrib>Rare, L</creatorcontrib><creatorcontrib>Tielsch, J M</creatorcontrib><creatorcontrib>Alpers, M P</creatorcontrib><creatorcontrib>West, K P</creatorcontrib><collection>Applied Social Sciences Index & Abstracts (ASSIA)</collection><jtitle>The Lancet (British edition)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Shankar, A H</au><au>Genton, B</au><au>Semba, R D</au><au>Baisor, M</au><au>Paino, J</au><au>Tamja, S</au><au>Adiguma, T</au><au>Wu, L</au><au>Rare, L</au><au>Tielsch, J M</au><au>Alpers, M P</au><au>West, K P</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effect of vitamin A supplementation on morbidity due to Plasmodium falciparum in young children in Papua New Guinea: a randomised trial</atitle><jtitle>The Lancet (British edition)</jtitle><date>1999-07-01</date><risdate>1999</risdate><volume>17</volume><spage>203</spage><epage>209</epage><pages>203-209</pages><issn>0140-6736</issn><coden>LANCAO</coden><abstract>Notes that many individuals at risk of malaria also have micronutrient deficiencies that may hamper protective immunity. Investigates the effect of vitamin A supplementation on malaria morbidity, and finds that it may be an effective low-cost strategy to lower morbidity in young children. Findings suggest that clinical episodes, spleen enlargement, and parasite density are influenced by different immunological mechanisms from infection and anaemia. (Original abstract - amended)</abstract></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0140-6736 |
| ispartof | The Lancet (British edition), 1999-07, Vol.17, p.203-209 |
| issn | 0140-6736 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_57754600 |
| source | Applied Social Sciences Index & Abstracts (ASSIA); ScienceDirect Journals (5 years ago - present); Business Source Complete |
| subjects | Double blind randomized controlled trials Malaria Papua New Guinea Prevention Vitamin A supplement Young children |
| title | Effect of vitamin A supplementation on morbidity due to Plasmodium falciparum in young children in Papua New Guinea: a randomised trial |
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