Opioid reinforcement in heroin-dependent volunteers during outpatient buprenorphine maintenance

This study examined the reinforcing effects of hydromorphone (HYD) (0, 4, 8, and 16 mg/70 kg i.m.) in heroin-dependent outpatient volunteers maintained on buprenorphine (BUP) at doses of 2, 4, and 8 mg, each for 2 weeks. Following a week of maintenance at each dose, volunteers received injections of...

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Veröffentlicht in:	Drug and alcohol dependence 1999-10, Vol.56 (3), p.191-203
Hauptverfasser:	Greenwald, Mark K., Johanson, Chris-Ellyn, Schuster, Charles R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Analysis of Variance Behavior, Addictive - drug therapy Behavior, Addictive - psychology Biological and medical sciences Buprenorphine Buprenorphine - therapeutic use Double-Blind Method Drug addictions Drug dependency Drug Synergism Female Heroin Heroin dependence Heroin Dependence - psychology Heroin Dependence - rehabilitation Heroin Dependence - urine Humans Hydromorphone Hydromorphone - administration & dosage Male Medical sciences Middle Aged Narcotic Antagonists - therapeutic use Narcotics - administration & dosage Opioids Outpatients - psychology Pupil - drug effects Reinforcement Reinforcement (Psychology) Surveys and Questionnaires Toxicology Treatment
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