Lithium Discontinuation and Subsequent Effectiveness

OBJECTIVE: Several reports have raised concern that the discontinuation of lithium may result in treatment resistance following recurrence of affective disorder. This report explores this possibility. METHOD: The data derive from a large, naturalistic follow-up of patients with major depressive diso...

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Veröffentlicht in:	The American journal of psychiatry 1998-07, Vol.155 (7), p.895-898
Hauptverfasser:	Coryell, William, Solomon, David, Leon, Andrew C., Akiskal, Hagop S., Keller, Martin B., Scheftner, William A., Mueller, Tim
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Bipolar Disorder - drug therapy Bipolar Disorder - prevention & control Discontinued Drug Administration Schedule Drug Resistance Drug therapy Effectiveness Female Follow-Up Studies Health care Humans Life Tables Lithium Lithium - administration & dosage Lithium - adverse effects Lithium - therapeutic use Male Manic depressive disorder Medical sciences Mental depression Neuropharmacology Pharmacology. Drug treatments Prospective Studies Psychiatry Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease) Psychology. Psychoanalysis. Psychiatry Psychopharmacology Psychotic Disorders - drug therapy Psychotic Disorders - prevention & control Recurrence Resumption Risk Factors Survival Analysis Treatment Outcome
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