Phenomenology and Outcome of Subjects With Early- and Adult-Onset Psychotic Mania

OBJECTIVE: This study examined clinical differences between subjects with early-onset and adult-onset psychotic mania. METHOD: Subjects were from an epidemiologically derived, hospitalized sample who met criteria for definite bipolar disorder after 24 months of follow-up and whose index episode had...

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Veröffentlicht in:The American journal of psychiatry 2000-02, Vol.157 (2), p.213-219
Hauptverfasser: Carlson, Gabrielle A., Bromet, Evelyn J., Sievers, Sylvia
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container_issue 2
container_start_page 213
container_title The American journal of psychiatry
container_volume 157
creator Carlson, Gabrielle A.
Bromet, Evelyn J.
Sievers, Sylvia
description OBJECTIVE: This study examined clinical differences between subjects with early-onset and adult-onset psychotic mania. METHOD: Subjects were from an epidemiologically derived, hospitalized sample who met criteria for definite bipolar disorder after 24 months of follow-up and whose index episode had been manic. Information collected regarding demographic characteristics, psychotic and depressive symptoms, childhood behavior problems and school functioning, substance alcohol use disorders, and episode recurrence for two subgroups were compared: those whose illness first emerged before age 21 (early onset) (N=23) and those whose first episode occurred after age 30 (adult onset) (N=30). RESULTS: A larger proportion of the early-onset subjects were male, had childhood behavior disorders, had substance abuse comorbidity, exhibited paranoia, and experienced complete episode remission less frequently during 24-month follow-up than the adult-onset subjects. CONCLUSIONS: These data add to the body of evidence that has suggested that many subjects with early-onset psychotic mania have a more severe and developmentally complicated subtype of bipolar disorder.
doi_str_mv 10.1176/appi.ajp.157.2.213
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METHOD: Subjects were from an epidemiologically derived, hospitalized sample who met criteria for definite bipolar disorder after 24 months of follow-up and whose index episode had been manic. Information collected regarding demographic characteristics, psychotic and depressive symptoms, childhood behavior problems and school functioning, substance alcohol use disorders, and episode recurrence for two subgroups were compared: those whose illness first emerged before age 21 (early onset) (N=23) and those whose first episode occurred after age 30 (adult onset) (N=30). RESULTS: A larger proportion of the early-onset subjects were male, had childhood behavior disorders, had substance abuse comorbidity, exhibited paranoia, and experienced complete episode remission less frequently during 24-month follow-up than the adult-onset subjects. 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subjects Achievement
Adolescent
Adult
Adult and adolescent clinical studies
Age Factors
Age of Onset
Alcoholism - diagnosis
Alcoholism - epidemiology
Biological and medical sciences
Bipolar Disorder - diagnosis
Bipolar Disorder - psychology
Child Behavior Disorders - diagnosis
Child Behavior Disorders - epidemiology
Cohort Studies
Comorbidity
Factors
Female
Follow-Up Studies
Hospitalization
Humans
Male
Mania
Medical sciences
Mental disorders
Middle Aged
Mood disorders
Odds Ratio
Outcome Assessment (Health Care)
Outcomes
Patients
Phenomenology
Prevalence
Psychiatric Status Rating Scales
Psychology
Psychology. Psychoanalysis. Psychiatry
Psychopathology. Psychiatry
Psychoses
Severity of Illness Index
Sex Factors
Substance-Related Disorders - diagnosis
Substance-Related Disorders - epidemiology
title Phenomenology and Outcome of Subjects With Early- and Adult-Onset Psychotic Mania
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