Phenomenology and Outcome of Subjects With Early- and Adult-Onset Psychotic Mania
OBJECTIVE: This study examined clinical differences between subjects with early-onset and adult-onset psychotic mania. METHOD: Subjects were from an epidemiologically derived, hospitalized sample who met criteria for definite bipolar disorder after 24 months of follow-up and whose index episode had...
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description | OBJECTIVE: This study examined clinical differences between subjects with early-onset and adult-onset psychotic mania. METHOD: Subjects were from an epidemiologically derived, hospitalized sample who met criteria for definite bipolar disorder after 24 months of follow-up and whose index episode had been manic. Information collected regarding demographic characteristics, psychotic and depressive symptoms, childhood behavior problems and school functioning, substance alcohol use disorders, and episode recurrence for two subgroups were compared: those whose illness first emerged before age 21 (early onset) (N=23) and those whose first episode occurred after age 30 (adult onset) (N=30). RESULTS: A larger proportion of the early-onset subjects were male, had childhood behavior disorders, had substance abuse comorbidity, exhibited paranoia, and experienced complete episode remission less frequently during 24-month follow-up than the adult-onset subjects. CONCLUSIONS: These data add to the body of evidence that has suggested that many subjects with early-onset psychotic mania have a more severe and developmentally complicated subtype of bipolar disorder. |
doi_str_mv | 10.1176/appi.ajp.157.2.213 |
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METHOD: Subjects were from an epidemiologically derived, hospitalized sample who met criteria for definite bipolar disorder after 24 months of follow-up and whose index episode had been manic. Information collected regarding demographic characteristics, psychotic and depressive symptoms, childhood behavior problems and school functioning, substance alcohol use disorders, and episode recurrence for two subgroups were compared: those whose illness first emerged before age 21 (early onset) (N=23) and those whose first episode occurred after age 30 (adult onset) (N=30). RESULTS: A larger proportion of the early-onset subjects were male, had childhood behavior disorders, had substance abuse comorbidity, exhibited paranoia, and experienced complete episode remission less frequently during 24-month follow-up than the adult-onset subjects. CONCLUSIONS: These data add to the body of evidence that has suggested that many subjects with early-onset psychotic mania have a more severe and developmentally complicated subtype of bipolar disorder.</description><identifier>ISSN: 0002-953X</identifier><identifier>EISSN: 1535-7228</identifier><identifier>DOI: 10.1176/appi.ajp.157.2.213</identifier><identifier>PMID: 10671389</identifier><identifier>CODEN: AJPSAO</identifier><language>eng</language><publisher>Washington, DC: American Psychiatric Publishing</publisher><subject>Achievement ; Adolescent ; Adult ; Adult and adolescent clinical studies ; Age Factors ; Age of Onset ; Alcoholism - diagnosis ; Alcoholism - epidemiology ; Biological and medical sciences ; Bipolar Disorder - diagnosis ; Bipolar Disorder - psychology ; Child Behavior Disorders - diagnosis ; Child Behavior Disorders - epidemiology ; Cohort Studies ; Comorbidity ; Factors ; Female ; Follow-Up Studies ; Hospitalization ; Humans ; Male ; Mania ; Medical sciences ; Mental disorders ; Middle Aged ; Mood disorders ; Odds Ratio ; Outcome Assessment (Health Care) ; Outcomes ; Patients ; Phenomenology ; Prevalence ; Psychiatric Status Rating Scales ; Psychology ; Psychology. Psychoanalysis. Psychiatry ; Psychopathology. Psychiatry ; Psychoses ; Severity of Illness Index ; Sex Factors ; Substance-Related Disorders - diagnosis ; Substance-Related Disorders - epidemiology</subject><ispartof>The American journal of psychiatry, 2000-02, Vol.157 (2), p.213-219</ispartof><rights>2000 INIST-CNRS</rights><rights>Copyright American Psychiatric Association Feb 2000</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-a454t-15822b0e90e8ff7cb18be27c0add2412de01ff81211cffd22c9f43f3cc9d999a3</citedby><cites>FETCH-LOGICAL-a454t-15822b0e90e8ff7cb18be27c0add2412de01ff81211cffd22c9f43f3cc9d999a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://psychiatryonline.org/doi/epdf/10.1176/appi.ajp.157.2.213$$EPDF$$P50$$Gappi$$H</linktopdf><linktohtml>$$Uhttps://psychiatryonline.org/doi/full/10.1176/appi.ajp.157.2.213$$EHTML$$P50$$Gappi$$H</linktohtml><link.rule.ids>314,780,784,2846,21617,21618,21619,27860,27915,27916,30991,77555,77560</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=1258829$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/10671389$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Carlson, Gabrielle A.</creatorcontrib><creatorcontrib>Bromet, Evelyn J.</creatorcontrib><creatorcontrib>Sievers, Sylvia</creatorcontrib><title>Phenomenology and Outcome of Subjects With Early- and Adult-Onset Psychotic Mania</title><title>The American journal of psychiatry</title><addtitle>Am J Psychiatry</addtitle><description>OBJECTIVE: This study examined clinical differences between subjects with early-onset and adult-onset psychotic mania. METHOD: Subjects were from an epidemiologically derived, hospitalized sample who met criteria for definite bipolar disorder after 24 months of follow-up and whose index episode had been manic. Information collected regarding demographic characteristics, psychotic and depressive symptoms, childhood behavior problems and school functioning, substance alcohol use disorders, and episode recurrence for two subgroups were compared: those whose illness first emerged before age 21 (early onset) (N=23) and those whose first episode occurred after age 30 (adult onset) (N=30). RESULTS: A larger proportion of the early-onset subjects were male, had childhood behavior disorders, had substance abuse comorbidity, exhibited paranoia, and experienced complete episode remission less frequently during 24-month follow-up than the adult-onset subjects. CONCLUSIONS: These data add to the body of evidence that has suggested that many subjects with early-onset psychotic mania have a more severe and developmentally complicated subtype of bipolar disorder.</description><subject>Achievement</subject><subject>Adolescent</subject><subject>Adult</subject><subject>Adult and adolescent clinical studies</subject><subject>Age Factors</subject><subject>Age of Onset</subject><subject>Alcoholism - diagnosis</subject><subject>Alcoholism - epidemiology</subject><subject>Biological and medical sciences</subject><subject>Bipolar Disorder - diagnosis</subject><subject>Bipolar Disorder - psychology</subject><subject>Child Behavior Disorders - diagnosis</subject><subject>Child Behavior Disorders - epidemiology</subject><subject>Cohort Studies</subject><subject>Comorbidity</subject><subject>Factors</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Hospitalization</subject><subject>Humans</subject><subject>Male</subject><subject>Mania</subject><subject>Medical sciences</subject><subject>Mental disorders</subject><subject>Middle Aged</subject><subject>Mood disorders</subject><subject>Odds Ratio</subject><subject>Outcome Assessment (Health Care)</subject><subject>Outcomes</subject><subject>Patients</subject><subject>Phenomenology</subject><subject>Prevalence</subject><subject>Psychiatric Status Rating Scales</subject><subject>Psychology</subject><subject>Psychology. Psychoanalysis. Psychiatry</subject><subject>Psychopathology. Psychiatry</subject><subject>Psychoses</subject><subject>Severity of Illness Index</subject><subject>Sex Factors</subject><subject>Substance-Related Disorders - diagnosis</subject><subject>Substance-Related Disorders - epidemiology</subject><issn>0002-953X</issn><issn>1535-7228</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2000</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>K30</sourceid><sourceid>7QJ</sourceid><recordid>eNp1kd9L5DAQx4N46PrjH_BBiie-tWYmzSZ5FPHuBGUVFX0LaZq4XbptbdqH_e8v6y54HPgwhAyf78zAh5AToBmAmF6arqsys-gy4CLDDIHtkAlwxlOBKHfJhFKKqeLsbZ8chLCIX8oE7pF9oFMBTKoJeXyYu6Zdxqrb91VimjKZjYONnaT1ydNYLJwdQvJaDfPkxvT1Kv1krsqxHtJZE9yQPISVnbdDZZN701TmiPzwpg7uePsekpdfN8_Xf9K72e_b66u71OQ8H1LgErGgTlEnvRe2AFk4FJaassQcsHQUvJeAANb7EtEqnzPPrFWlUsqwQ3Kxmdv17cfowqCXVbCurk3j2jFoLnKUMR_Bs__ARTv2TbxNI9I8l1NBI_TzOwg4SBZLqkjhhrJ9G0LvvO76amn6lQaq10702omOTmJKaNTRSQydbkePxdKV_0Q2EiJwvgVMsKb2vWlsFb445FLiGrvcYJ87vs77fvNfhfGkjw</recordid><startdate>20000201</startdate><enddate>20000201</enddate><creator>Carlson, Gabrielle A.</creator><creator>Bromet, Evelyn J.</creator><creator>Sievers, Sylvia</creator><general>American Psychiatric Publishing</general><general>American Psychiatric Association</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>HAWNG</scope><scope>HBMBR</scope><scope>IBDFT</scope><scope>K30</scope><scope>PAAUG</scope><scope>PAWHS</scope><scope>PAWZZ</scope><scope>PAXOH</scope><scope>PBHAV</scope><scope>PBQSW</scope><scope>PBYQZ</scope><scope>PCIWU</scope><scope>PCMID</scope><scope>PCZJX</scope><scope>PDGRG</scope><scope>PDWWI</scope><scope>PETMR</scope><scope>PFVGT</scope><scope>PGXDX</scope><scope>PIHIL</scope><scope>PISVA</scope><scope>PJCTQ</scope><scope>PJTMS</scope><scope>PLCHJ</scope><scope>PMHAD</scope><scope>PNQDJ</scope><scope>POUND</scope><scope>PPLAD</scope><scope>PQAPC</scope><scope>PQCAN</scope><scope>PQCMW</scope><scope>PQEME</scope><scope>PQHKH</scope><scope>PQMID</scope><scope>PQNCT</scope><scope>PQNET</scope><scope>PQSCT</scope><scope>PQSET</scope><scope>PSVJG</scope><scope>PVMQY</scope><scope>PZGFC</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7QJ</scope></search><sort><creationdate>20000201</creationdate><title>Phenomenology and Outcome of Subjects With Early- and Adult-Onset Psychotic Mania</title><author>Carlson, Gabrielle A. ; Bromet, Evelyn J. ; Sievers, Sylvia</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a454t-15822b0e90e8ff7cb18be27c0add2412de01ff81211cffd22c9f43f3cc9d999a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2000</creationdate><topic>Achievement</topic><topic>Adolescent</topic><topic>Adult</topic><topic>Adult and adolescent clinical studies</topic><topic>Age Factors</topic><topic>Age of Onset</topic><topic>Alcoholism - diagnosis</topic><topic>Alcoholism - epidemiology</topic><topic>Biological and medical sciences</topic><topic>Bipolar Disorder - diagnosis</topic><topic>Bipolar Disorder - psychology</topic><topic>Child Behavior Disorders - diagnosis</topic><topic>Child Behavior Disorders - epidemiology</topic><topic>Cohort Studies</topic><topic>Comorbidity</topic><topic>Factors</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Hospitalization</topic><topic>Humans</topic><topic>Male</topic><topic>Mania</topic><topic>Medical sciences</topic><topic>Mental disorders</topic><topic>Middle Aged</topic><topic>Mood disorders</topic><topic>Odds Ratio</topic><topic>Outcome Assessment (Health Care)</topic><topic>Outcomes</topic><topic>Patients</topic><topic>Phenomenology</topic><topic>Prevalence</topic><topic>Psychiatric Status Rating Scales</topic><topic>Psychology</topic><topic>Psychology. Psychoanalysis. Psychiatry</topic><topic>Psychopathology. Psychiatry</topic><topic>Psychoses</topic><topic>Severity of Illness Index</topic><topic>Sex Factors</topic><topic>Substance-Related Disorders - diagnosis</topic><topic>Substance-Related Disorders - epidemiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Carlson, Gabrielle A.</creatorcontrib><creatorcontrib>Bromet, Evelyn J.</creatorcontrib><creatorcontrib>Sievers, Sylvia</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Periodicals Index Online Segment 13</collection><collection>Periodicals Index Online Segment 14</collection><collection>Periodicals Index Online Segment 27</collection><collection>Periodicals Index Online</collection><collection>Primary Sources Access—Foundation Edition (Plan E) - West</collection><collection>Primary Sources Access (Plan D) - International</collection><collection>Primary Sources Access & Build (Plan A) - MEA</collection><collection>Primary Sources Access—Foundation Edition (Plan E) - Midwest</collection><collection>Primary Sources Access—Foundation Edition (Plan E) - Northeast</collection><collection>Primary Sources Access (Plan D) - Southeast</collection><collection>Primary Sources Access (Plan D) - North Central</collection><collection>Primary Sources Access—Foundation Edition (Plan E) - Southeast</collection><collection>Primary Sources Access (Plan D) - South Central</collection><collection>Primary Sources Access & Build (Plan A) - UK / I</collection><collection>Primary Sources Access (Plan D) - Canada</collection><collection>Primary Sources Access (Plan D) - EMEALA</collection><collection>Primary Sources Access—Foundation Edition (Plan E) - North Central</collection><collection>Primary Sources Access—Foundation Edition (Plan E) - South Central</collection><collection>Primary Sources Access & Build (Plan A) - International</collection><collection>Primary Sources Access—Foundation Edition (Plan E) - International</collection><collection>Primary Sources Access (Plan D) - West</collection><collection>Periodicals Index Online Segments 1-50</collection><collection>Primary Sources Access (Plan D) - APAC</collection><collection>Primary Sources Access (Plan D) - Midwest</collection><collection>Primary Sources Access (Plan D) - MEA</collection><collection>Primary Sources Access—Foundation Edition (Plan E) - Canada</collection><collection>Primary Sources Access—Foundation Edition (Plan E) - UK / I</collection><collection>Primary Sources Access—Foundation Edition (Plan E) - EMEALA</collection><collection>Primary Sources Access & Build (Plan A) - APAC</collection><collection>Primary Sources Access & Build (Plan A) - Canada</collection><collection>Primary Sources Access & Build (Plan A) - West</collection><collection>Primary Sources Access & Build (Plan A) - EMEALA</collection><collection>Primary Sources Access (Plan D) - Northeast</collection><collection>Primary Sources Access & Build (Plan A) - Midwest</collection><collection>Primary Sources Access & Build (Plan A) - North Central</collection><collection>Primary Sources Access & Build (Plan A) - Northeast</collection><collection>Primary Sources Access & Build (Plan A) - South Central</collection><collection>Primary Sources Access & Build (Plan A) - Southeast</collection><collection>Primary Sources Access (Plan D) - UK / I</collection><collection>Primary Sources Access—Foundation Edition (Plan E) - APAC</collection><collection>Primary Sources Access—Foundation Edition (Plan E) - MEA</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><collection>Applied Social Sciences Index & Abstracts (ASSIA)</collection><jtitle>The American journal of psychiatry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Carlson, Gabrielle A.</au><au>Bromet, Evelyn J.</au><au>Sievers, Sylvia</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Phenomenology and Outcome of Subjects With Early- and Adult-Onset Psychotic Mania</atitle><jtitle>The American journal of psychiatry</jtitle><addtitle>Am J Psychiatry</addtitle><date>2000-02-01</date><risdate>2000</risdate><volume>157</volume><issue>2</issue><spage>213</spage><epage>219</epage><pages>213-219</pages><issn>0002-953X</issn><eissn>1535-7228</eissn><coden>AJPSAO</coden><abstract>OBJECTIVE: This study examined clinical differences between subjects with early-onset and adult-onset psychotic mania. METHOD: Subjects were from an epidemiologically derived, hospitalized sample who met criteria for definite bipolar disorder after 24 months of follow-up and whose index episode had been manic. Information collected regarding demographic characteristics, psychotic and depressive symptoms, childhood behavior problems and school functioning, substance alcohol use disorders, and episode recurrence for two subgroups were compared: those whose illness first emerged before age 21 (early onset) (N=23) and those whose first episode occurred after age 30 (adult onset) (N=30). RESULTS: A larger proportion of the early-onset subjects were male, had childhood behavior disorders, had substance abuse comorbidity, exhibited paranoia, and experienced complete episode remission less frequently during 24-month follow-up than the adult-onset subjects. CONCLUSIONS: These data add to the body of evidence that has suggested that many subjects with early-onset psychotic mania have a more severe and developmentally complicated subtype of bipolar disorder.</abstract><cop>Washington, DC</cop><pub>American Psychiatric Publishing</pub><pmid>10671389</pmid><doi>10.1176/appi.ajp.157.2.213</doi><tpages>7</tpages></addata></record> |
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subjects | Achievement Adolescent Adult Adult and adolescent clinical studies Age Factors Age of Onset Alcoholism - diagnosis Alcoholism - epidemiology Biological and medical sciences Bipolar Disorder - diagnosis Bipolar Disorder - psychology Child Behavior Disorders - diagnosis Child Behavior Disorders - epidemiology Cohort Studies Comorbidity Factors Female Follow-Up Studies Hospitalization Humans Male Mania Medical sciences Mental disorders Middle Aged Mood disorders Odds Ratio Outcome Assessment (Health Care) Outcomes Patients Phenomenology Prevalence Psychiatric Status Rating Scales Psychology Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Psychoses Severity of Illness Index Sex Factors Substance-Related Disorders - diagnosis Substance-Related Disorders - epidemiology |
title | Phenomenology and Outcome of Subjects With Early- and Adult-Onset Psychotic Mania |
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