Cognitive Processing, Discovery of Meaning, CD4 Decline, and AIDS-Related Mortality Among Bereaved HIV-Seropositive Men

This study investigated whether finding meaning in response to an HIV-related stressor was associated with changes in immune status and health. Forty HIV-seropositive men who had recently experienced an AIDS-related bereavement completed interviews assessing cognitive processing and finding meaning...

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Veröffentlicht in:Journal of consulting and clinical psychology 1998-12, Vol.66 (6), p.979-986
Hauptverfasser: Bower, Julienne E, Kemeny, Margaret E, Taylor, Shelley E, Fahey, John L
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container_end_page 986
container_issue 6
container_start_page 979
container_title Journal of consulting and clinical psychology
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creator Bower, Julienne E
Kemeny, Margaret E
Taylor, Shelley E
Fahey, John L
description This study investigated whether finding meaning in response to an HIV-related stressor was associated with changes in immune status and health. Forty HIV-seropositive men who had recently experienced an AIDS-related bereavement completed interviews assessing cognitive processing and finding meaning after the loss and provided blood samples for a 2- to 3-year follow-up. AIDS-related mortality over an extended follow-up was determined from death certificates. As predicted, men who engaged in cognitive processing were more likely to find meaning from the loss. Furthermore, men who found meaning showed less rapid declines in CD4 T cell levels and lower rates of AIDS-related mortality (all p s < .05), independent of health status at baseline, health behaviors, and other potential confounds. These results suggest that positive responses to stressful events, specifically the discovery of meaning, may be linked to positive immunologic and health outcomes.
doi_str_mv 10.1037/0022-006X.66.6.979
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Forty HIV-seropositive men who had recently experienced an AIDS-related bereavement completed interviews assessing cognitive processing and finding meaning after the loss and provided blood samples for a 2- to 3-year follow-up. AIDS-related mortality over an extended follow-up was determined from death certificates. As predicted, men who engaged in cognitive processing were more likely to find meaning from the loss. Furthermore, men who found meaning showed less rapid declines in CD4 T cell levels and lower rates of AIDS-related mortality (all p s &lt; .05), independent of health status at baseline, health behaviors, and other potential confounds. 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Forty HIV-seropositive men who had recently experienced an AIDS-related bereavement completed interviews assessing cognitive processing and finding meaning after the loss and provided blood samples for a 2- to 3-year follow-up. AIDS-related mortality over an extended follow-up was determined from death certificates. As predicted, men who engaged in cognitive processing were more likely to find meaning from the loss. Furthermore, men who found meaning showed less rapid declines in CD4 T cell levels and lower rates of AIDS-related mortality (all p s &lt; .05), independent of health status at baseline, health behaviors, and other potential confounds. These results suggest that positive responses to stressful events, specifically the discovery of meaning, may be linked to positive immunologic and health outcomes.</description><subject>Acquired immune deficiency syndrome</subject><subject>Acquired Immunodeficiency Syndrome - immunology</subject><subject>Acquired Immunodeficiency Syndrome - mortality</subject><subject>Acquired Immunodeficiency Syndrome - psychology</subject><subject>Adult</subject><subject>AIDS</subject><subject>Bereavement</subject><subject>Biological and medical sciences</subject><subject>CD4 Lymphocyte Count</subject><subject>Cognition &amp; reasoning</subject><subject>Cognitive processing</subject><subject>Fundamental and applied biological sciences. 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source Applied Social Sciences Index & Abstracts (ASSIA); MEDLINE; EBSCOhost APA PsycARTICLES; Periodicals Index Online
subjects Acquired immune deficiency syndrome
Acquired Immunodeficiency Syndrome - immunology
Acquired Immunodeficiency Syndrome - mortality
Acquired Immunodeficiency Syndrome - psychology
Adult
AIDS
Bereavement
Biological and medical sciences
CD4 Lymphocyte Count
Cognition & reasoning
Cognitive processing
Fundamental and applied biological sciences. Psychology
Health
Health Knowledge, Attitudes, Practice
HIV
HIV Seropositivity - psychology
Homosexuality, Male - psychology
Homosexuality, Male - statistics & numerical data
Human
Human immunodeficiency virus
Humans
Illness and personality
Illness, stress and coping
Immune system
Life Change Events
Longitudinal Studies
Los Angeles
Male
Meaning
Men
Middle Aged
Mortality
Outcomes
Psychological Tests
Psychology
Psychology and medicine
Psychology. Psychoanalysis. Psychiatry
Psychology. Psychophysiology
Sexual Behavior
Stress
Stress, Psychological - immunology
Stress, Psychological - psychology
Substance-Related Disorders
Survival Rate
title Cognitive Processing, Discovery of Meaning, CD4 Decline, and AIDS-Related Mortality Among Bereaved HIV-Seropositive Men
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