Efficacy of RTS,S/AS02 malaria vaccine against Plasmodium falciparum infection in semi-immune adult men in the Gambia: a randomised trial

Malaria caused by Plasmodium falciparum continues to be a major cause of disease and death in sub-Saharan Africa. 306 men aged 18-45 years were randomly assigned 3 doses of either RTS,S/AS02 or rabies vaccine (control). Volunteers were given sulfadoxine /pyrimethamine 2 weeks before dose 3, and kept...

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Veröffentlicht in:	The Lancet (British edition) 2001-12, Vol.8, p.1927-1934
Hauptverfasser:	Bojang, K A, Milligan, P J M, Pinder, M, Vigneron, L, Alloueche, A, Kester, K E, Ballou, W R, Conway, D J, Reece, W H H, Gothard, P, Yamuah, L, Delchambre, M, Voss, G, Greenwood, B M, Hill, A, McAdam, K P W J, Tornieporth, N, Cohen, J D, Doherty, T
Format:	Artikel
Sprache:	eng
Schlagworte:	Efficacy Gambia Immunological status Malaria Men Randomized controlled trials Vaccines
Online-Zugang:	Volltext
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