Biochemical and Neurotransmitter Changes Implicated in Alcohol-Induced Brain Damage in Chronic or ‘Binge Drinking’ Alcohol Abuse

The brain damage, which occurs after either chronic alcoholization or binge drinking regimes, shows distinct biochemical and neurotransmitter differences. An excessive amount of glutamate is released into specific brain regions during binge drinking (in excess of 4- to 5-fold of the normal basal con...

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Veröffentlicht in:	Alcohol and alcoholism (Oxford) 2009-03, Vol.44 (2), p.128-135
Hauptverfasser:	Ward, Roberta J., Lallemand, Frédéric, de Witte, Philippe
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease Alcohol withdrawal syndrome Alcoholism Alcoholism - pathology Amino Acids - physiology Animals Binge drinking Brain Chemistry - drug effects Brain damage Brain Damage, Chronic - chemically induced Brain Damage, Chronic - pathology Humans Macrophages - drug effects Macrophages - metabolism Neuroglia - drug effects Neuroglia - metabolism Neurotransmitter Agents - metabolism Neurotransmitters Phosphorylation
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