Toxic effects of carbendazim and n-butyl isocyanate, metabolites of the fungicide benomyl, on early development in the African clawed frog, Xenopus laevis

We investigated the toxic effects of carbendazim and n-butyl isocyanate (BIC), metabolites of the fungicide benomyl, on development in the African clawed frog, Xenopus laevis. To test the toxic effects, frog embryo teratogenesis assays using Xenopus were performed. Embryos were exposed to various co...

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Veröffentlicht in:	Environmental toxicology 2008-02, Vol.23 (1), p.131-144
Hauptverfasser:	Yoon, Chun-Sik, Jin, Jung-Hyo, Park, Joo-Hung, Yeo, Chang-Yeol, Kim, Song-Ja, Hwang, Yong-Gi, Hong, Sung-Jin, Cheong, Seon-Woo
Format:	Artikel
Sprache:	eng
Schlagworte:	Amphibia. Reptilia analysis Animal, plant and microbial ecology Animals Applied ecology benomyl Benomyl - toxicity Benzimidazoles Benzimidazoles - toxicity Biological and medical sciences brain Carbamates Carbamates - toxicity carbendazim cell adhesion DNA Primers drug effects early development Ecotoxicology, biological effects of pollution Embryo, Nonmammalian Embryo, Nonmammalian - drug effects embryology Environmental Exposure eyes FETAX frogs Fundamental and applied biological sciences. Psychology fungicides Fungicides, Industrial Fungicides, Industrial - toxicity gene expression General aspects genetics growth & development Isocyanates Isocyanates - toxicity lethal concentration 50 Lethal Dose 50 malformation metabolism metabolites n-butyl isocyanate Nervous System Nervous System - embryology Nervous System - metabolism Nervous System - ultrastructure probit analysis Reverse Transcriptase Polymerase Chain Reaction RNA RNA - analysis toxicity ultrastructure Vertebrates: general zoology, morphology, phylogeny, systematics, cytogenetics, geographical distribution Xenopus Xenopus laevis Xenopus laevis - embryology Xenopus laevis - genetics Xenopus laevis - growth & development
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