Bioreduction of [alpha]-chloroacetophenone by whole cells of marine fungi

The asymmetric reduction of 2-chloro-1-phenylethanone (1) by seven strains of marine fungi was evaluated and afforded (S)-(-)-2-chloro-1-phenylethanol with, in the best case, an enantiomeric excess of 50% and an isolated yield of 60%. The ability of marine fungi to catalyse the reduction was directl...

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Veröffentlicht in:	Biotechnology letters 2009-10, Vol.31 (10), p.1559-1563
Hauptverfasser:	Rocha, Lenilson C, Ferreira, Hercules V, Pimenta, Eli F, Berlinck, Roberto GS, Seleghim, Mirna HR, Javaroti, Darci CD, Sette, Lara D, Bonugli, Rafaella C, Porto, Andre LM
Format:	Artikel
Sprache:	eng
Schlagworte:	Asymmetry Biotechnology Cellular biology Fungi Glucose Marine Marine biology Reduction Sea water Seawater Strain Substrates
Online-Zugang:	Volltext
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