Biodegradation Studies of Rosin-Glycerol Ester Derivative
A rosin glycerol derivative was prepared by esterification of rosin with glycerol at 220-240°C in the presence of zinc as catalyst. The product was evaluated for different physicochemical properties. Films were prepared by melt molding with castor oil (20% w/w of the derivative) as an external plast...
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| Veröffentlicht in: | Journal of bioactive and compatible polymers 1999-07, Vol.14 (4), p.344-360 |
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| container_issue | 4 |
| container_start_page | 344 |
| container_title | Journal of bioactive and compatible polymers |
| container_volume | 14 |
| creator | Sahu, N. H. Mandaogade, P. M. Deshmukh, A. M. Meghre, V. S. Dorle, A. K. |
| description | A rosin glycerol derivative was prepared by esterification of rosin with glycerol at 220-240°C in the presence of zinc as catalyst. The product was evaluated for different physicochemical properties. Films were prepared by melt molding with castor oil (20% w/w of the derivative) as an external plasticizer. The in vitro and in vivo biodegradation studies were performed on films as well as on powder. The in vitro studies were performed with microorganisms, enzymes and different buffer solutions while in vivo studies were performed on rabbits by subdermal implantation of rosin ester films. The results of all the studies showed that rosin glycerol ester undergoes biodegradation and follows surface erosion mechanism. |
| doi_str_mv | 10.1177/088391159901400405 |
| format | Article |
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H. ; Mandaogade, P. M. ; Deshmukh, A. M. ; Meghre, V. S. ; Dorle, A. K.</creator><creatorcontrib>Sahu, N. H. ; Mandaogade, P. M. ; Deshmukh, A. M. ; Meghre, V. S. ; Dorle, A. K.</creatorcontrib><description>A rosin glycerol derivative was prepared by esterification of rosin with glycerol at 220-240°C in the presence of zinc as catalyst. The product was evaluated for different physicochemical properties. Films were prepared by melt molding with castor oil (20% w/w of the derivative) as an external plasticizer. The in vitro and in vivo biodegradation studies were performed on films as well as on powder. The in vitro studies were performed with microorganisms, enzymes and different buffer solutions while in vivo studies were performed on rabbits by subdermal implantation of rosin ester films. The results of all the studies showed that rosin glycerol ester undergoes biodegradation and follows surface erosion mechanism.</description><identifier>ISSN: 0883-9115</identifier><identifier>EISSN: 1530-8030</identifier><identifier>DOI: 10.1177/088391159901400405</identifier><identifier>CODEN: JBCPEV</identifier><language>eng</language><publisher>Thousand Oaks, CA: Sage Publications</publisher><subject>Biological and medical sciences ; Catalysts ; Derivatives ; Enzymes ; Esterification ; Esters ; Glycerol ; Medical sciences ; Microorganisms ; Solutions ; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases ; Technology. Biomaterials. 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The results of all the studies showed that rosin glycerol ester undergoes biodegradation and follows surface erosion mechanism.</description><subject>Biological and medical sciences</subject><subject>Catalysts</subject><subject>Derivatives</subject><subject>Enzymes</subject><subject>Esterification</subject><subject>Esters</subject><subject>Glycerol</subject><subject>Medical sciences</subject><subject>Microorganisms</subject><subject>Solutions</subject><subject>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</subject><subject>Technology. Biomaterials. 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| identifier | ISSN: 0883-9115 |
| ispartof | Journal of bioactive and compatible polymers, 1999-07, Vol.14 (4), p.344-360 |
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| language | eng |
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| source | SAGE Complete |
| subjects | Biological and medical sciences Catalysts Derivatives Enzymes Esterification Esters Glycerol Medical sciences Microorganisms Solutions Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Technology. Biomaterials. Equipments Zinc |
| title | Biodegradation Studies of Rosin-Glycerol Ester Derivative |
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