Simple structured polydimethylsiloxane microvalve actuated by external air pressure

Abstract This article describes a simple structured microvalve made of polydimethylsiloxane (PDMS) and glass. For easy operation, the microvalve is actuated by external air pressure. The microvalve is fabricated by replica moulding using a negative photoresist (SU-8) as the mould. For low cost and b...

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Veröffentlicht in:Proceedings of the Institution of Mechanical Engineers. Part C, Journal of mechanical engineering science Journal of mechanical engineering science, 2006-08, Vol.220 (8), p.1283-1288
Hauptverfasser: Lee, S-W, Kim, D-J, Ahn, Y, Chai, Y G
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container_title Proceedings of the Institution of Mechanical Engineers. Part C, Journal of mechanical engineering science
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creator Lee, S-W
Kim, D-J
Ahn, Y
Chai, Y G
description Abstract This article describes a simple structured microvalve made of polydimethylsiloxane (PDMS) and glass. For easy operation, the microvalve is actuated by external air pressure. The microvalve is fabricated by replica moulding using a negative photoresist (SU-8) as the mould. For low cost and biocompatibility, PDMS is used as the chip material. The PDMS valve is bonded to a Pyrex glass substrate using an O2 plasma surface treatment. It was found that no leakage occurs under a valve-actuating air pressure of 0.35 MPa when the injection pressure of liquid in the microchannel of the valve is 0.01-0.04 MPa. The fabricated microvalve is applied to a microfluidic chip having one inlet and two outlet channels. Fluid flow is controlled by the microvalve.
doi_str_mv 10.1243/09544062JMES177
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For easy operation, the microvalve is actuated by external air pressure. The microvalve is fabricated by replica moulding using a negative photoresist (SU-8) as the mould. For low cost and biocompatibility, PDMS is used as the chip material. The PDMS valve is bonded to a Pyrex glass substrate using an O2 plasma surface treatment. It was found that no leakage occurs under a valve-actuating air pressure of 0.35 MPa when the injection pressure of liquid in the microchannel of the valve is 0.01-0.04 MPa. The fabricated microvalve is applied to a microfluidic chip having one inlet and two outlet channels. 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Fluid flow is controlled by the microvalve.</description><subject>Biocompatibility</subject><subject>Borosilicate glass</subject><subject>External pressure</subject><subject>Fluid dynamics</subject><subject>Fluid flow</subject><subject>Glass substrates</subject><subject>Mechanical engineering</subject><subject>Molding (process)</subject><subject>Molds</subject><subject>Pneumatics</subject><subject>Polydimethylsiloxane</subject><subject>Pressure</subject><subject>Product design</subject><subject>Replicas</subject><subject>Silicone resins</subject><subject>Surface treatment</subject><subject>Valves</subject><issn>0954-4062</issn><issn>2041-2983</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>BENPR</sourceid><recordid>eNqF0c1LwzAUAPAgCs7p2WtR8GRdPpvmKGN-MfEwPZc0e9WOdK1JO9b_3pR5kMEwlwTe772X5CF0SfAdoZxNsBKc44S-vM4WRMojNKKYk5iqlB2j0RCNh_ApOvN-hcOiiRihxaKsGguRb11n2s7BMmpq2y_LCtqv3vrS1lu9hqgqjas32m4g0sHpNsC8j2DbgltrG-nSRY0D70OJc3RSaOvh4ncfo4-H2fv0KZ6_PT5P7-exYUq0sRRSLYnKQQhulMxzGc6cEaFUmghSkBSrgqWGayGYTI0CqjXkKVWS4NQINkY3u7qNq7878G1Wld6AteHCdeczllAmGVX_QqooThJOA7zag6u6G94XDOMKCylZQNeHEFFSJolQcug52anwb947KLLGlZV2fUZwNgws2xtYyLjdZXj9CX9qHuA_RPCVEQ</recordid><startdate>20060801</startdate><enddate>20060801</enddate><creator>Lee, S-W</creator><creator>Kim, D-J</creator><creator>Ahn, Y</creator><creator>Chai, Y G</creator><general>SAGE Publications</general><general>SAGE PUBLICATIONS, INC</general><scope>AAYXX</scope><scope>CITATION</scope><scope>7TB</scope><scope>8FD</scope><scope>F28</scope><scope>FR3</scope><scope>3V.</scope><scope>7XB</scope><scope>88I</scope><scope>8AF</scope><scope>8AO</scope><scope>8FE</scope><scope>8FG</scope><scope>8FK</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>L6V</scope><scope>M2P</scope><scope>M7S</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PTHSS</scope><scope>Q9U</scope></search><sort><creationdate>20060801</creationdate><title>Simple structured polydimethylsiloxane microvalve actuated by external air pressure</title><author>Lee, S-W ; 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2041-2983
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subjects Biocompatibility
Borosilicate glass
External pressure
Fluid dynamics
Fluid flow
Glass substrates
Mechanical engineering
Molding (process)
Molds
Pneumatics
Polydimethylsiloxane
Pressure
Product design
Replicas
Silicone resins
Surface treatment
Valves
title Simple structured polydimethylsiloxane microvalve actuated by external air pressure
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