In vivo evaluation and in vitro metabolism of leuprolide in mice--mass spectrometry-based biomarker measurement for efficacy and toxicity

The study of pharmacologically active peptides is central for the understanding of cancer and the development of novel therapeutic approaches. In this context, both qualitative and quantitative determination of bioactive peptides in biological fluids/tissues and their effect on endogenous factors (e...

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Veröffentlicht in:Journal of mass spectrometry. 2008-10, Vol.43 (10), p.1381-1392
Hauptverfasser: Sofianos, Zacharias D, Katsila, Theodora, Kostomitsopoulos, Nikolaos, Balafas, Vaggelis, Matsoukas, John, Tselios, Theodoros, Tamvakopoulos, Constantin
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Sprache:eng
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