Creation of a biologically active interleukin-5 monomer

INTERLEUKIN-5 (IL-5) specifically induces the differentiation of eosinophils, which are important in host defence and the patho-genesis of allergies and asthma 1,2 . Structurally, IL-5 is a unique member of the short-chain helical-bundle subfamily of cytokines whose canonical motif contains four hel...

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Veröffentlicht in:Nature (London) 1996-02, Vol.379 (6566), p.652-655
Hauptverfasser: Dickason, Richard R., Huston, David P.
Format: Artikel
Sprache:eng
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