Brominating Oxidants Generated by Human Eosinophils

Eosinophils are white blood cells that in humans are found in association with helminthic infections and various inflammatory disease processes. These cells contain a unique lysosomal peroxidase that oxidizes halides to generate highly reactive and toxic hypohalous acids. Although chloride is found...

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Veröffentlicht in:	Science (American Association for the Advancement of Science) 1986-10, Vol.234 (4773), p.200-203
Hauptverfasser:	Weiss, Stephen J., Test, Samuel T., Eckmann, Carel M., Roos, Dirk, Regiani, Sandra
Format:	Artikel
Sprache:	eng
Schlagworte:	Azides Biochemistry Biological and medical sciences Blood Blood cells Bromates - metabolism Bromides Bromides (Chemistry) Bromides - metabolism Bromination Bromine - metabolism Chlorides Eosinophils Eosinophils - enzymology Fundamental and applied biological sciences. Psychology Halides Humans Hypochlorous Acid - metabolism Infections Inflammation Leukocytes Lipids Lipopolysaccharides Medical research Molecular and cellular biology Neutrophils Neutrophils - enzymology Oxidation-Reduction Peroxidases - blood Physiological aspects Superoxides - metabolism White blood cells
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