Viral kinetics and exhaled droplet size affect indoor transmission dynamics of influenza infection

The purpose of this paper was to investigate the effects of viral kinetics and exhaled droplet size on indoor transmission dynamics of influenza infection. The target cell-limited model with delayed virus production was adopted to strengthen the inner mechanisms of virus infection on human epithelia...

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Veröffentlicht in:Indoor air 2009-10, Vol.19 (5), p.401-413
Hauptverfasser: Chen, S. C., Chio, C. P., Jou, L. J., Liao, C. M.
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Sprache:eng
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Zusammenfassung:The purpose of this paper was to investigate the effects of viral kinetics and exhaled droplet size on indoor transmission dynamics of influenza infection. The target cell-limited model with delayed virus production was adopted to strengthen the inner mechanisms of virus infection on human epithelial cell. The particle number and volume involved in the viral kinetics were linked with Wells-Riley mathematical equation to quantify the infection risk. We investigated population dynamics in a specific elementary school by using the seasonal susceptible - exposed - infected - recovery (SEIR) model. We found that exhaled pulmonary bioaerosol of sneeze (particle diameter
ISSN:0905-6947
1600-0668
DOI:10.1111/j.1600-0668.2009.00603.x