Selenium tissue distribution changes after ethanol exposure during gestation and lactation: Selenite as a therapy

Ethanol consumption affects maternal nutrition and antioxidant status together with the future health of their progeny. Selenium (Se) is a trace element with antioxidant activity; we will study the effect of ethanol in dams on Se bioavailability, antioxidant balance and gestational parameters. We al...

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Veröffentlicht in:	Food and chemical toxicology 2009-10, Vol.47 (10), p.2484-2489
Hauptverfasser:	Jotty, K., Ojeda, M.L., Nogales, F., Rubio, J.M., Murillo, M.L., Carreras, O.
Format:	Artikel
Sprache:	eng
Schlagworte:	alcohol abuse Alcoholism and acute alcohol poisoning animal models Animals antioxidant activity antioxidants Antioxidants - administration & dosage Antioxidants - pharmacokinetics atomic absorption spectrometry Biological and medical sciences blood serum Central Nervous System Depressants - toxicity cortex dams (mothers) dietary mineral supplements dietary minerals Disease Models, Animal Drug Interactions Ethanol Ethanol - toxicity Female free radical scavengers Gestation gestation period Glutathione peroxidase heart Lactation Lactation - drug effects Lactation - metabolism liver Longevity - drug effects Male mammary glands Maternal Exposure - adverse effects maternal nutrition Medical sciences muscles nutrient availability Pregnancy progeny Rats Rats, Wistar salivary glands selenites Selenium Sodium Selenite - administration & dosage Sodium Selenite - pharmacokinetics spleen Tissue Distribution - drug effects Toxicology Wistar rats
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