Encapsulation and quantification of multiple dye guests in unmodified poly(amidoamine) dendrimers as a function of generation

This work illustrates the remarkable ability of amine-terminated PAMAM dendrimers to entrap multiple guest molecules. While previous encapsulation studies with dendritic polymers demonstrated multi-dye uptake, the dendrimers required extensive synthetic modification. This study utilizes unmodified P...

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Veröffentlicht in:	Talanta (Oxford) 2009-06, Vol.78 (4), p.1489-1491
Hauptverfasser:	Kline, Katrina K., Morgan, Elizabeth J., Norton, Lisa K., Tucker, Sheryl A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical chemistry Chemistry Coloring Agents - isolation & purification Dendrimers Drug Compounding Encapsulation Exact sciences and technology Fluorescence Phenols Polyamines - chemical synthesis Polyamines - chemistry Spectrometric and optical methods Structure-Activity Relationship Water Pollutants, Chemical - isolation & purification
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description	This work illustrates the remarkable ability of amine-terminated PAMAM dendrimers to entrap multiple guest molecules. While previous encapsulation studies with dendritic polymers demonstrated multi-dye uptake, the dendrimers required extensive synthetic modification. This study utilizes unmodified PAMAM dendrimers to encapsulate multiple phenol blue molecules. Quantitative data on the uptake capacity and robustness of association is presented.
doi_str_mv	10.1016/j.talanta.2009.01.051
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source	MEDLINE; ScienceDirect Journals (5 years ago - present)
subjects	Analytical chemistry Chemistry Coloring Agents - isolation & purification Dendrimers Drug Compounding Encapsulation Exact sciences and technology Fluorescence Phenols Polyamines - chemical synthesis Polyamines - chemistry Spectrometric and optical methods Structure-Activity Relationship Water Pollutants, Chemical - isolation & purification
title	Encapsulation and quantification of multiple dye guests in unmodified poly(amidoamine) dendrimers as a function of generation
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